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DC Field | Value | Language |
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dc.contributor.author | Santos García, Diego | - |
dc.contributor.author | De Deus Fonticoba, Teresa | - |
dc.contributor.author | Paz González, Jose | - |
dc.contributor.author | Cores Bartolomé, Carlos | - |
dc.contributor.author | Valdés Aymerich, Lorena | - |
dc.contributor.author | Muñoz Enríquez, J. G. | - |
dc.contributor.author | Suárez, Ester | - |
dc.contributor.author | Jesús, Silvia | - |
dc.contributor.author | Aguilar, Miquel | - |
dc.contributor.author | Pastor, Pau | - |
dc.contributor.author | Planellas, Lluís | - |
dc.contributor.author | Cosgaya, Marina | - |
dc.contributor.author | García Caldentey, Juan | - |
dc.contributor.author | Caballol, Núria | - |
dc.contributor.author | Legarda, Ines | - |
dc.contributor.author | Hernández Vara, Jorge | - |
dc.contributor.author | Cabo, Iria | - |
dc.contributor.author | López Manzanares, Lydia | - |
dc.contributor.author | González Aramburu, Isabel | - |
dc.contributor.author | Ávila Rivera, Maria Asunción | - |
dc.contributor.author | Catalán, María José | - |
dc.contributor.author | Nogueira, Victor | - |
dc.contributor.author | Puente, Victor | - |
dc.contributor.author | García Moreno, Jose Manuel | - |
dc.contributor.author | Borrué, Carmen | - |
dc.contributor.author | Solano Vila, Berta | - |
dc.contributor.author | Álvarez Sauco, Maria | - |
dc.contributor.author | Vela, Lydia | - |
dc.contributor.author | Escalante Arroyo, Sonia | - |
dc.contributor.author | Cubo, Esther | - |
dc.contributor.author | Carrillo Padilla, Francisco | - |
dc.contributor.author | Martínez Castrillo, Juan | - |
dc.contributor.author | Sánchez Alonso, Pilar | - |
dc.contributor.author | Alonso Losada, Maria Gema | - |
dc.contributor.author | López Ariztegui, Nuria | - |
dc.contributor.author | Gastón, Itziar | - |
dc.contributor.author | Kulisevsky, Jaime | - |
dc.contributor.author | Blázquez Estrada, M. | - |
dc.contributor.author | Seijo Martínez, Manuel | - |
dc.contributor.author | Rúiz Martínez, Javier | - |
dc.date.accessioned | 2021-09-21T16:34:06Z | - |
dc.date.available | 2021-09-21T16:34:06Z | - |
dc.date.issued | 2021-05-15 | - |
dc.identifier.issn | 2042-0080 | - |
dc.identifier.uri | http://hdl.handle.net/2445/180192 | - |
dc.description.abstract | Introduction: In a degenerative disorder such as Parkinson's disease (PD), it is important to establish clinical stages that allow to know the course of the disease. Our aim was to analyze whether a scale combining Hoehn and Yahr's motor stage (H&Y) and the nonmotor symptoms burden (NMSB) (assessed by the nonmotor symptoms scale (NMSS)) provides information about the disability and the patient's quality of life (QoL) with regard to a defined clinical stage. Materials and methods: Cross-sectional study in which 603 PD patients from the COPPADIS cohort were classified according to H&Y (1, stage I; 2, stage II; 3, stage III; 4, stage IV/V) and NMSB (A: NMSS = 0-20; B: NMSS = 21-40; C: NMSS = 41-70; D: NMSS ≥ 71) in 16 stages (HY.NMSB, from 1A to 4D). QoL was assessed with the PDQ-39SI, PQ-10, and EUROHIS-QOL8 and disability with the Schwab&England ADL (Activities of Daily Living) scale. Results: A worse QoL and greater disability were observed at a higher stage of H&Y and NMSB (p < 0.0001). Combining both (HY.NMSB), patients in stages 1C and 1D and 2C and 2D had significantly worse QoL and/or less autonomy for ADL than those in stages 2A and 2B and 3A and 3B, respectively (p < 0.005; e.g., PDQ-39SI in 1D [n = 15] vs 2A [n = 101]: 28.6 ± 17.1 vs 7.9 ± 5.8; p < 0.0001). Conclusion: The HY.NMSB scale is simple and reflects the degree of patient involvement more accurately than the HΨ Patients with a lower H&Y stage may be more affected if they have a greater NMS burden. | - |
dc.format.extent | 16 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Hindawi | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1155/2021/8871549 | - |
dc.relation.ispartof | Parkinson's Disease, 2021 | - |
dc.relation.uri | https://doi.org/10.1155/2021/8871549 | - |
dc.rights | cc-by (c) Santos García, Diego et al., 2021 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Malaltia de Parkinson | - |
dc.subject.other | Parkinson's disease | - |
dc.title | Staging Parkinson's Disease Combining Motor and Nonmotor Symptoms Correlates with Disability and Quality of Life. | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 713303 | - |
dc.date.updated | 2021-09-21T16:34:06Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 34094501 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) |
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File | Description | Size | Format | |
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713303.pdf | 1.41 MB | Adobe PDF | View/Open |
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