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http://hdl.handle.net/2445/181570
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DC Field | Value | Language |
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dc.contributor.author | Casaroli Marano, Ricardo Pedro | - |
dc.contributor.author | Bernal Morales, Carolina | - |
dc.contributor.author | Chamorro López, Lillian | - |
dc.contributor.author | Dotti Boada, Marina | - |
dc.contributor.author | Figueroa Vercellino, Juan P. | - |
dc.contributor.author | Alforja, Socorro | - |
dc.date.accessioned | 2021-12-01T15:37:43Z | - |
dc.date.available | 2021-12-01T15:37:43Z | - |
dc.date.issued | 2020-11-21 | - |
dc.identifier.issn | 2090-004X | - |
dc.identifier.uri | http://hdl.handle.net/2445/181570 | - |
dc.description.abstract | The current treatment of neovascular age-related macular degeneration (nAMD) generates an excessive care pressure in the public health system. The search for a satisfactory treatment regimen, whose anatomical and functional stability may be achieved, is a challenge and a goal to be reached. We analyzed the outcomes in a patient cohort under fixed regimen treatment with intravitreal aflibercept (IVA). A retrospective study, with at least 1-year follow-up, in consecutive treated unselected naïve patients was carried out. Standard protocol was performed and evaluated at baseline, month 4 (after loading dose, LD), and month 12 (after fixed bimonthly regimen). One hundred six patients (123 eyes) aged 80.3 ± 7.7 years were included, receiving 6.8 ± 0.7 IVA. Visual acuity gain after LD was 5.5 ± 12.0 letters (). At month 12, 23 eyes (18.7%) gained ≥15 letters and 58 (47.1%) had best-corrected visual acuity ≥20/40 (70 letters). The improvement in visual acuity was lower in patients with polypoidal choroidal vasculopathy (+4.9 ± 18.1 letters; p = 0.2544) and somewhat higher in patients with retinal angiomatous proliferation (+5.4 ± 12.3 letters; ). Dry macula was present in only 9.8% of cohort at baseline vs. 69.7% at month 12 (). Atrophy was the most observed complication and related to the elderly patients. The average of follow-up visits was 3 ± 0.5. Functional and anatomical improvement were observed with IVA in a fixed bimonthly regimen treatment after LD, with results maintained up to one year with a good compliance. The fixed bimonthly regimen optimized patient management and logistic issues. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Hindawi | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1155/2020/8848336 | - |
dc.relation.ispartof | Journal of Ophthalmology, 2020, vol. 2020, num. 8848336 | - |
dc.relation.uri | https://doi.org/10.1155/2020/8848336 | - |
dc.rights | cc-by (c) Casaroli Marano, Ricardo Pedro et al., 2020 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) | - |
dc.subject.classification | Trastorns de la visió | - |
dc.subject.other | Vision disorders | - |
dc.title | Fixed Regimen Treatment in Unselected Naive Patients Cohort with Neovascular Age-Related Macular Degeneration | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 709431 | - |
dc.date.updated | 2021-12-01T15:37:43Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) |
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File | Description | Size | Format | |
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709431.pdf | 1.29 MB | Adobe PDF | View/Open |
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