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Title: A Novel, Extremely Bioavailable Cocrystal of Pterostilbene
Author: Bofill, Lídia
Barbas Cañero, Rafael
de-Sande, Dafne
Font Bardia, Ma. Mercedes
Rafols Llach, Clara
Albertí, Joan
Prohens López, Rafael
Keywords: Cristal·lografia
Issue Date: 3-Mar-2021
Publisher: American Chemical Society
Abstract: New multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening. Among the coformers tested, picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats, which converts the new cocrystal into a very promising candidate for new formulations of pterostilbene with improved performance.
Note: Versió postprint del document publicat a:
It is part of: Crystal Growth & Design, 2021, vol. 21, num. 4, p. 2315-2323
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ISSN: 1528-7483
Appears in Collections:Articles publicats en revistes (Centres Científics i Tecnològics de la Universitat de Barcelona (CCiTUB))
Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada)
Articles publicats en revistes (Enginyeria Química i Química Analítica)

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