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http://hdl.handle.net/2445/183529| Title: | A Novel, Extremely Bioavailable Cocrystal of Pterostilbene |
| Author: | Bofill, Lídia Barbas Cañero, Rafael Sande, Dafne de Font Bardia, Ma. Mercedes Rafols Llach, Clara Albertí, Joan Prohens López, Rafael |
| Keywords: | Cristal·lografia Crystallography |
| Issue Date: | 3-Mar-2021 |
| Publisher: | American Chemical Society |
| Abstract: | New multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening. Among the coformers tested, picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats, which converts the new cocrystal into a very promising candidate for new formulations of pterostilbene with improved performance. |
| Note: | Versió postprint del document publicat a: https://doi.org/10.1021/acs.cgd.0c01716 |
| It is part of: | Crystal Growth & Design, 2021, vol. 21, num. 4, p. 2315-2323 |
| URI: | http://hdl.handle.net/2445/183529 |
| Related resource: | https://doi.org/10.1021/acs.cgd.0c01716 |
| ISSN: | 1528-7483 |
| Appears in Collections: | Articles publicats en revistes (Centres Científics i Tecnològics de la Universitat de Barcelona (CCiTUB)) Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) Articles publicats en revistes (Enginyeria Química i Química Analítica) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 710755.pdf | 1.16 MB | Adobe PDF | View/Open |
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