Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/184214
Title: | Molecular characterization of imported and autochthonous dengue in northeastern spain |
Author: | Navero-Castillejos, Jessica Benítez, Rosa M. Torner Gràcia, Núria Muñoz Gutiérrez, José Camprubí Ferrer, Daniel Peiró Mestres, Aida Sulleiro, Elena Silgado, Aroa Gonzalo, Verónica Falgueras, Teresa Alejo-Cancho, Izaskun Roldán, Montserrat Plasencia, Virginia Albarracín, Rosa Pérez, Josefa Navarro, Alexander Calderón, Ana Rubio, Rosa Navarro, Mireia Micó, Miguel Llaberia Marcual, Jaume Navarro, María Barrachina, Josep Vilamala, Anna Martí, Carmina Pulido, María Ángeles Sanchez Seco, María Paz Vázquez, Ana Martínez, Ana Jané, Mireia Martínez, Miguel Julián |
Keywords: | Dengue Microbiologia Malalties infeccioses Dengue Microbiology Communicable diseases |
Issue Date: | 23-Sep-2021 |
Publisher: | MDPI |
Abstract: | Dengue is the most significant arbovirus worldwide and a public health threat to nonendemic areas in which Aedes vectors are present. Autochthonous dengue transmission has been reported in several European countries in the last decade. Infected travelers from endemic regions arriving to areas colonized by Aedes albopictus in Europe need to be monitored in surveillance and control programs. We aimed to perform molecular characterization of RT-PCR-positive dengue cases detected in Catalonia, northeastern Spain, from 2013 to 2018. The basic demographic information and the geographical regions of importation were also analyzed. One-hundred four dengue cases were studied (103 imported infections and the first autochthonous case in our region). The dengue virus strains detected were serotyped and genotyped using molecular methods, and phylogenetic analyses were conducted. All four dengue serotypes were detected in travelers, including up to 10 different genotypes, reflecting the global circulation of dengue in endemic areas. The primary travel-related case of the 2018 autochthonous transmission was not identified, but the molecular analysis revealed dengue serotype 1, genotype I of Asian origin. Our results highlight the diversity of imported dengue virus strains and the role of molecular epidemiology in supporting arbovirus surveillance programs. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/v13101910 |
It is part of: | Viruses, 2021, vol. 13, num. 10, p. 1-17 |
URI: | http://hdl.handle.net/2445/184214 |
Related resource: | https://doi.org/10.3390/v13101910 |
ISSN: | 1999-4915 |
Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (ISGlobal) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
715585.pdf | 3.48 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License