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http://hdl.handle.net/2445/186040| Title: | Aminocatalyzed reactions of aldehydes with chiral nitroalkenes |
| Author: | Cascales Jiménez, Victor Carneros García, Héctor Castro Álvarez, Alejandro Costa i Arnau, Anna M. Vilarrasa i Llorens, Jaume |
| Keywords: | Reaccions d'addició Aldehids Catalitzadors Addition reactions Aldehydes Catalysts |
| Issue Date: | 11-Jan-2021 |
| Publisher: | American Chemical Society |
| Abstract: | Chiral nitroalkenes are used for the first time in Michael additions of aldehydes, catalyzed by pyrrolidine derivatives. They yield the same major stereoisomer with either (S)-proline or (R)-proline, but this asymmetric induction does not overcome the effect of sterically more congested catalysts. Nitrocyclobutane intermediates are often formed, which are more stable than those from (E)-1-nitro-2-phenylethene. The cyclobutanes and final products were characterized by 2D NMR and chemical correlations |
| Note: | Versió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.0c03609 |
| It is part of: | Organic Letters, 2021, vol. 23, num. 3, p. 651-655 |
| URI: | http://hdl.handle.net/2445/186040 |
| Related resource: | https://doi.org/10.1021/acs.orglett.0c03609 |
| ISSN: | 1523-7060 |
| Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 710915.pdf | 1.19 MB | Adobe PDF | View/Open |
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