Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/18628
Title: Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis
Author: Salerno, Francesco
Gerbes, Alexander
Ginès i Gibert, Pere
Wong, Florence
Arroyo, Vicente
Keywords: Cirrosi hepàtica
Malalties dels ronyons
Diagnòstic
Medicina preventiva
Terapèutica
Hepatic cirrhosis
Kidney diseases
Diagnosis
Preventive medicine
Therapeutics
Issue Date: 2007
Publisher: BMJ Group
Abstract: Hepatorenal syndrome (HRS) is a serious complication of end-stage liver disease, occurring mainly in patients with advanced cirrhosis and ascites, who have marked circulatory dysfunction,1 as well as in patients with acute liver failure.2 In spite of its functional nature, HRS is associated with a poor prognosis,3 4 and the only effective treatment is liver transplantation. During the 56th Meeting of the American Association for the Study of Liver Diseases, the International Ascites Club held a Focused Study Group (FSG) on HRS for the purpose of reporting the results of an international workshop and to reach a consensus on a new definition, criteria for diagnosis and recommendations on HRS treatment. A similar workshop was held in Chicago in 1994 in which standardised nomenclature and diagnostic criteria for refractory ascites and HRS were established.5 The introduction of innovative treatments and improvements in our understanding of the pathogenesis of HRS during the previous decade led to an increasing need to undertake a new consensus meeting. This paper reports the scientific rationale behind the new definitions and recommendations. The international workshop included four issues debated by four panels of experts (see Acknowledgements). The issues were: (1) evidence-based HRS pathogenesis; (2) treatment of HRS using vasoconstrictors; (3) other HRS treatments using transjugular intrahepatic portosystemic stent-shunt (TIPS) and extracorporeal albumin dialysis (ECAD); and (4) new definitions and diagnostic criteria for HRS and recommendations for its treatment.
Note: Reproducció digital del document publicat a: http://dx.doi.org/10.1136/gut.2006.107789
It is part of: Gut, 2007, vol. 56, núm. 9, p. 1310-1318
URI: http://hdl.handle.net/2445/18628
ISSN: 0017-5749
Appears in Collections:Articles publicats en revistes (Medicina)

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