Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/18653
Title: CO2 wedged hepatic venography in the evaluation of portal hypertension.
Author: Debernardi-Venon, W.
Bandi, J. C.
García Pagán, Juan Carlos
Moitinho, E.
Andreu, V.
Real, M.
Escorsell i Mañosa, M. Àngels
Montanyá, X.
Bosch i Genover, Jaume
Keywords: Hipertensió portal
Hemodinàmica
Diagnòstic per la imatge
Cirrosi hepàtica
Portal hypertension
Hemodynamics
Diagnostic imaging
Hepatic cirrhosis
Issue Date: 2000
Publisher: BMJ Group
Abstract: BACKGROUND/AIMS/METHODS During hepatic vein catheterisation, in addition to measurement of hepatic venous pressure gradient (HVPG), iodine wedged retrograde portography can be easily obtained. However, it rarely allows correct visualisation of the portal vein. Recently, CO2 has been suggested to allow better angiographic demonstration of the portal vein than iodine. In this study we investigated the efficacy of CO2 compared with iodinated contrast medium for portal vein imaging and its role in the evaluation of portal hypertension in a series of 100 patients undergoing hepatic vein catheterisation, 71 of whom had liver cirrhosis. RESULTS In the overall series, CO2 venography was markedly superior to iodine, allowing correct visualisation of the different segments of the portal venous system. In addition, CO2, but not iodine, visualised portal-systemic collaterals in 34 patients. In cirrhosis, non-visualisation of the portal vein on CO2 venography occurred in 11 cases; four had portal vein thrombosis and five had communications between different hepatic veins. Among non-cirrhotics, lack of portal vein visualisation had a 90% sensitivity, 88% specificity, 94% negative predictive value, and 83% positive predictive value in the diagnosis of pre-sinusoidal portal hypertension. CONCLUSIONS Visualisation of the venous portal system by CO2 venography is markedly superior to iodine. The use of CO2 wedged portography is a useful and safe complementary procedure during hepatic vein catheterisation which may help to detect portal thrombosis. Also, lack of demonstration of the portal vein in non-cirrhotic patients strongly suggests the presence of pre-sinusoidal portal hypertension.
Note: Reproducció digital del document publicat a: http://dx.doi.org/10.1136/gut.46.6.856
It is part of: Gut, 2000, vol. 46, núm 6, p. 856-860
URI: http://hdl.handle.net/2445/18653
ISSN: 0017-5749
Appears in Collections:Articles publicats en revistes (Medicina)

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