Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/186605
Title: | Chromatin organization and function in Drosophila |
Author: | Llorens-Giralt, Palmira Camilleri‑Robles, Carlos Corominas, Montserrat (Corominas Guiu) Climent-Cantó, Paula |
Keywords: | Regulació genètica Cromatina Drosòfila Genetic regulation Chromatin Drosophila |
Issue Date: | 8-Sep-2021 |
Publisher: | MDPI |
Abstract: | Eukaryotic genomes are packaged into high-order chromatin structures organized in discrete territories inside the cell nucleus, which is surrounded by the nuclear envelope acting as a barrier. This chromatin organization is complex and dynamic and, thus, determining the spatial and temporal distribution and folding of chromosomes within the nucleus is critical for understanding the role of chromatin topology in genome function. Primarily focusing on the regulation of gene expression, we review here how the genome of Drosophila melanogaster is organized into the cell nucleus, from small scale histone-DNA interactions to chromosome and lamina interactions in the nuclear space. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/cells10092362 |
It is part of: | Cells, 2021, vol. 10, num. 9, p. 2362 |
URI: | http://hdl.handle.net/2445/186605 |
Related resource: | https://doi.org/10.3390/cells10092362 |
ISSN: | 2073-4409 |
Appears in Collections: | Articles publicats en revistes (Genètica, Microbiologia i Estadística) |
Files in This Item:
File | Description | Size | Format | |
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716077.pdf | 1.28 MB | Adobe PDF | View/Open |
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