Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/18879
Title: Mechanical properties of viral capsids
Author: Zandi, Roya
Reguera, D. (David)
Keywords: Física mèdica
Nanoestructures
Medical physics
Nanostructures
Issue Date: 2005
Publisher: The American Physical Society
Abstract: Viruses are known to tolerate wide ranges of pH and salt conditions and to withstand internal pressures as high as 100 atmospheres. In this paper we investigate the mechanical properties of viral capsids, calling explicit attention to the inhomogeneity of the shells that is inherent to their discrete and polyhedral nature. We calculate the distribution of stress in these capsids and analyze their response to isotropic internal pressure (arising, for instance, from genome confinement and/or osmotic activity). We compare our results with appropriate generalizations of classical (i.e., continuum) elasticity theory. We also examine competing mechanisms for viral shell failure, e.g., in-plane crack formation vs radial bursting. The biological consequences of the special stabilities and stress distributions of viral capsids are also discussed.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1103/PhysRevE.72.021917
It is part of: Physical Review e, 2004, vol. 72, núm. 2, p. 021917-1-021917-12
URI: http://hdl.handle.net/2445/18879
ISSN: 1063-651X
Appears in Collections:Articles publicats en revistes (Física de la Matèria Condensada)

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