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http://hdl.handle.net/2445/199544
Title: | Update about Oralair® as a treatment for grass pollen allergic rhinitis |
Author: | Klimek, Ludger Brehler, Randolf Mösges, Ralph Demoly, Pascal Mullol i Miret, Joaquim Wang, De Yun O'Hehir, Robyn Didier, Alain Kopp, Matthias Volkmar Bos, Catherine Karagiannis, Efstratios |
Keywords: | Rinitis Gramínies Antihistamínics Rhinitis Grasses Antihistamines |
Issue Date: | 15-Jun-2022 |
Publisher: | Taylor and Francis |
Abstract: | Sublingual immunotherapy (SLIT) is a well-tolerated, safe, and effective approach to treating allergic rhinitis (AR). Oralair (R) is a five-grass pollen SLIT tablet containing natural pollen allergens from five of the major grass species responsible for seasonal AR due to grass pollen allergy. Recommended use is in a pre-coseasonal regimen, starting daily treatment approximately 4 months before the start of the pollen season, with treatment then continued daily throughout the season; treatment should continue for 3-5 y. Clinical efficacy and safety of Oralair (R) in patients with grass pollen-induced AR has been demonstrated in a comprehensive clinical development program of randomized controlled trials. Effectiveness has been substantiated in subsequent observational studies with sustained efficacy following treatment cessation and a favorable level of adherence, quality of life, benefit, and satisfaction for the patients. Supportive evidence for a benefit in reducing the risk or delaying the development of allergic asthma is emerging. |
Note: | Reproducció del document publicat a: https://doi.org/10.1080/21645515.2022.2066424 |
It is part of: | Human Vaccines & Immunotherapeutics, 2022, vol. 18, num. 5 |
URI: | http://hdl.handle.net/2445/199544 |
Related resource: | https://doi.org/10.1080/21645515.2022.2066424 |
ISSN: | 2164-554X |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
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Update_about_Oralair.pdf | 730.62 kB | Adobe PDF | View/Open |
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