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DC Field | Value | Language |
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dc.contributor.author | Khoury, Nadine | - |
dc.contributor.author | Martínez, María Ángeles | - |
dc.contributor.author | Paz-Graniel I | - |
dc.contributor.author | Martínez-González, Miguel Ángel, 1957- | - |
dc.contributor.author | Corella Piquer, Dolores | - |
dc.contributor.author | Castañer, Olga | - |
dc.contributor.author | Martínez, J. Alfredo | - |
dc.contributor.author | Alonso Gómez, Ángel M. | - |
dc.contributor.author | Wärnberg, Julia | - |
dc.contributor.author | Vioque, Jesús | - |
dc.contributor.author | Romaguera, Dora | - |
dc.contributor.author | López Miranda, José | - |
dc.contributor.author | Estruch Riba, Ramon | - |
dc.contributor.author | Tinahones, Francisco J. | - |
dc.contributor.author | Lapetra, José | - |
dc.contributor.author | Serra Majem, Lluís | - |
dc.contributor.author | Bueno Cavanillas, Aurora | - |
dc.contributor.author | Tur, Josep A. | - |
dc.contributor.author | Cinza Sanjurjo, Sergio | - |
dc.contributor.author | Pintó Sala, Xavier | - |
dc.contributor.author | Gaforio, José J. | - |
dc.contributor.author | Matía Martín, Pilar | - |
dc.contributor.author | Vidal i Cortada, Josep | - |
dc.contributor.author | Vázquez, Clotilde | - |
dc.contributor.author | Daimiel, Lidia | - |
dc.contributor.author | Ros Rahola, Emilio | - |
dc.contributor.author | Sayon Orea, Carmen | - |
dc.contributor.author | Sorlí, José V. | - |
dc.contributor.author | Pérez Vega, Karla Alejandra | - |
dc.contributor.author | García Ríos, Antonio | - |
dc.contributor.author | Gómez Bellvert, Nuria | - |
dc.contributor.author | Gómez Gracia, Enrique | - |
dc.contributor.author | Zulet, M. Angeles | - |
dc.contributor.author | Chaplin, Alice | - |
dc.contributor.author | Casas Rodríguez, Rosa M. | - |
dc.contributor.author | Salcedo Bellido, Inmaculada | - |
dc.contributor.author | Tojal Sierra, Lucas | - |
dc.contributor.author | Bernal López, M. Rosa | - |
dc.contributor.author | Vázquez Ruiz, Zenaida | - |
dc.contributor.author | Asensio, Eva M. | - |
dc.contributor.author | Goday Arnó, Albert | - |
dc.contributor.author | Peña Orihuela, Patricia J. | - |
dc.contributor.author | Signes Pastor, Antonio J. | - |
dc.contributor.author | Garcia-Arellano, Ana | - |
dc.contributor.author | Fitó Colomer, Montserrat | - |
dc.contributor.author | Babio, Nancy | - |
dc.contributor.author | Salas Salvadó, Jordi | - |
dc.date.accessioned | 2023-08-01T11:19:03Z | - |
dc.date.available | 2023-08-01T11:19:03Z | - |
dc.date.issued | 2023-03-25 | - |
dc.identifier.issn | 0013-9351 | - |
dc.identifier.uri | http://hdl.handle.net/2445/201403 | - |
dc.description.abstract | Introduction: The principal source of exposure to Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzo-p-furans (PCDD/Fs) in humans comes from food intake. PCDD/Fs, are a family of potential endocrine disruptors and have been associated with different chronic diseases such as diabetes and hypertension. However, studies assessing the relationship between dietary exposure to PCDD/Fs and adiposity or obesity status in a middle-aged population are limited. Objective: To assess cross-sectionally and longitudinally the associations between estimated dietary intake (DI) of PCDD/Fs and body mass index (BMI), waist circumference, and the prevalence/incidence of obesity and abdominal obesity in a middle-aged population. Methods: In 5899 participants aged 55-75 years (48% women) living with overweight/obesity from the PREDIMED-plus cohort, PCDD/Fs DI was estimated using a 143-item validated food-frequency questionnaire, and the levels of food PCDD/F expressed as Toxic Equivalents (TEQ). Consequently, cross-sectional and prospective associations between baseline PCDD/Fs DI (in pgTEQ/week) and adiposity or obesity status were assessed at baseline and after 1-year follow-up using multivariable cox, logistic or linear regression models. Results: Compared to participants in the first PCDD/F DI tertile, those in the highest tertile presented a higher BMI (β-coefficient [confidence interval]) (0.43kg/m2 [0.22; 0.64]; P-trend <0.001), a higher waist circumference (1.11 cm [0.55; 1.66]; P-trend <0.001), and a higher prevalence of obesity and abdominal obesity (1.05 [1.01; 1.09] and 1.02 [1.00; 1.03]; P-trend = 0.09 and 0.027, respectively). In the prospective analysis, participants in the top PCDD/F DI baseline tertile showed an increase in waist circumference compared with those in the first tertile after 1-year of follow-up (β-coefficient 0.37 cm [0.06; 0.70]; P-trend = 0.015). Conclusion: Higher DI of PCDD/Fs was positively associated with adiposity parameters and obesity status at baseline and with changes in waist circumference after 1-year of follow-up in subjects living with overweight/obesity. Further large prospective studies using a different population with longer follow-up periods are warranted in the future to strengthen our results. Keywords: Abdominal obesity; Adiposity; Endocrine disrupting chemicals; Obesity; Polychlorinated dibenzo-p-furans (PCDD/F). | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1016/j.envres.2023.115697 | - |
dc.relation.ispartof | Environmental Research, 2023, vol. 227, p. 115697 | - |
dc.relation.uri | https://doi.org/10.1016/j.envres.2023.115697 | - |
dc.rights | cc-by (c) Khoury, Nadine et al., 2023 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Obesitat | - |
dc.subject.classification | Teixit adipós | - |
dc.subject.classification | Disruptors endocrins | - |
dc.subject.classification | Dioxines | - |
dc.subject.classification | Persones de mitjana edat | - |
dc.subject.classification | Dieta | - |
dc.subject.classification | Diet | - |
dc.subject.other | Obesity | - |
dc.subject.other | Adipose tissues | - |
dc.subject.other | Endocrine disrupting chemicals | - |
dc.subject.other | Dioxins | - |
dc.subject.other | Middle aged persons | - |
dc.title | Dietary intake of polychlorinated dibenzo-p-dioxins and furans, adiposity and obesity status | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 733179 | - |
dc.date.updated | 2023-08-01T11:19:03Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 36972775 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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