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Issue DateTitleAuthor(s)
12-Feb-20141,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studiesDi Pietro, O.; Viayna, Elisabet; Vicente García, Esther; Bartolini, Manuela; Ramón, Rosario; Juárez-Jiménez, Jordi; Clos, Victòria; Pérez Fernández, Belén; Andrisano, Vincenza; Luque Garriga, F. Xavier; Lavilla Grífols, Rodolfo; Muñoz-Torrero López-Ibarra, Diego
23-Sep-2013Undifferentiated and differentiated PC12 cells protected by huprines against injury induced by hydrogen peroxidePera, Marta; Camps García, Pelayo; Muñoz-Torrero López-Ibarra, Diego; Pérez Fernández, Belén; Badía, A. (Albert); Clos, Victòria
27-Mar-2014Synthesis and multi-target biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agentsViayna, Elisabet; Sola, Irene; Bartolini, Manuela; De Simone, Angela; Tapia-Rojas, Cheril; Serrano, Felipe G.; Sabaté Lagunas, Raimon; Juárez-Jiménez, Jordi; Pérez Fernández, Belén; Luque Garriga, F. Xavier; Andrisano, Vincenza; Clos, Victòria; Inestrosa, Nibaldo C.; Muñoz-Torrero López-Ibarra, Diego
1-Oct-2014Shogaol-huprine hybrids: Dual antioxidant and anticholinesterase agents with beta-amyloid and tau anti-aggregating propertiesPérez Areales, Francisco Javier; Di Pietro, O.; Espargaró Colomé, Alba; Vallverdú i Queralt, Anna; Galdeano Cantador, Carlos; Ragusa, Ilaria M.; Viayna, Elisabet; Guillou, Catherine; Clos, Victòria; Pérez Fernández, Belén; Sabaté Lagunas, Raimon; Lamuela Raventós, Rosa Ma.; Luque Garriga, F. Xavier; Muñoz-Torrero López-Ibarra, Diego
12-Sep-2014Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting beta-amyloid, tau, and cholinesterase pathologiesDi Pietro, O.; Pérez Areales, Francisco Javier; Juárez-Jiménez, Jordi; Espargaró Colomé, Alba; Clos, Victòria; Pérez Fernández, Belén; Lavilla Grífols, Rodolfo; Sabaté Lagunas, Raimon; Luque Garriga, F. Xavier; Muñoz-Torrero López-Ibarra, Diego
13-Nov-2015Multicomponent-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activityDi Pietro, O.; Vicente García, Esther; Taylor, Martin C.; Berenguer, Diana; Viayna, Elisabet; Lanzoni, Anna; Sola, Irene; Sayago, Helena; Riera Lizandra, Ma. Cristina; Fisa Saladrigas, Roser; Clos, Victòria; Pérez Fernández, Belén; Kelly, John M.; Lavilla Grífols, Rodolfo; Muñoz-Torrero López-Ibarra, Diego
1-Dec-2014Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprinesSola, Irene; Artigas, Albert; Taylor, Martin C.; Gbedema, Stephen Y.; Pérez Fernández, Belén; Clos, Victòria; Wright, Colin W.; Kelly, John M.; Muñoz-Torrero López-Ibarra, Diego
11-Mar-2018Increasing polarity in tacrine and huprine derivatives: Potent anticholinesterase agents for the treatment of myasthenia gravisGaldeano Cantador, Carlos; Coquelle, Nicolas; Cieslikiewicz-Bouet, Monika; Bartolini, Manuela; Pérez, Belén; Clos, Victòria; Silman, Israel; Jean, Ludovic; Colletier, Jacques-Philippe; Renard, Pierre-Yves; Muñoz-Torrero López-Ibarra, Diego
4-Sep-2018Neuroprotective effects of the multitarget agent AVCRI104P3 in brain of middle-aged miceRelat, Julia; Come, Julio; Perez, B.; Camps García, Pelayo; Muñoz-Torrero López-Ibarra, Diego; Badia, Albert; Giménez Llort, Lydia; Clos, Victòria
2021Clock/Sleep-Dependent Learning and Memory in Male 3xTg-AD Mice at Advanced Disease Stages and Extrinsic Effects of Huprine X and the Novel Multitarget Agent AVCRI104P3Giménez Llort, Lydia; Santana-Santana, Mikel; Ratia, Míriam; Pérez, Belén; Camps García, Pelayo; Muñoz-Torrero López-Ibarra, Diego; Badía, A. (Albert); Clos, Victòria