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Title: | Prognostic Factors Associated with Acute Heart Failure in Patients Admitted for COVID-19: Analysis of the SEMI-COVID-19 Registry |
Author: | Méndez Bailón, Manuel Lorenzo Villalba, Noel Garcia Onrubia, Jorge Rubio Rivas, Manuel Nuñez Rodriguez, Maria Reyes Pascual Pérez, María de los Díaz Pedroche, Carmen Fonseca Aizpuru, Eva Villalba Garcia, Maria García García, Gema Pesqueira Fontán, Paula Artero, Arturo Montero Hernandez, Esther Alcalá Pedrajas, José Giner Galvan, Vicente Monge Monge, Daniel Letona Giménez, Laura García Gómez, Miriam Martínez Cilleros, Carmen Puente Ruiz, Nuria Escobar Sevilla, Joaquin Gómez Méndez, Raquel Ramos Rincón, José Gomez Huelgas, Ricardo SEMI-COVID-19 Network |
Keywords: | COVID-19 Insuficiència cardíaca COVID-19 Heart failure |
Issue Date: | 12-Jul-2023 |
Publisher: | MDPI AG |
Abstract: | Introduction: Since the beginning of the COVID-19 pandemic in March 2020, an intimate relationship between this disease and cardiovascular diseases has been seen. However, few studies assess the development of heart failure during this infection. This study aims to determine the predisposing factors for the development of heart failure (HF) during hospital admission of COVID-19 patients. Methodology: A retrospective and multicenter study of patients with HF admitted for COVID-19 in 150 Spanish hospitals (SEMI-COVID-19 Registry). A bivariate analysis was performed to relate the different variables evaluated in patients developing heart failure during hospital admission. A multivariate analysis including the most relevant clinical variables obtained in bivariate analyses to predict the outcome of heart failure was performed. Results: A total of 16.474 patients hospitalized for COVID-19 were included (57.5% men, mean age 67 years), 958 of them (5.8%) developed HF during hospitalization. The risk factors for HF development were: age (odds ratio [OR]): 1.042; confidence interval 95% (CI 95%): 1.035-1.050; p < 0.001), atrial fibrillation (OR: 2.022; CI 95%: 1.697-2.410; p < 0.001), BMI > 30 kg/m(2) (OR: 1.460 CI 95%: 1.230-1.733; p < 0001), and peripheral vascular disease (OR: 1.564; CI 95%: 1.217-2.201; p < 0.001). Patients who developed HF had a higher rate of mortality (54.1% vs. 19.1%, p < 0.001), intubation rate (OR: 2,36; p < 0.001), and ICU admissions (OR: 2.38; p < 0001). Conclusions: Patients who presented a higher risk of developing HF were older with cardiovascular risk factors. The risk factors for HF development were age, atrial fibrillation, obesity, and peripheral vascular disease. In addition, patients who developed HF more frequently required to be intubated or admitted to the ICU. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/jcm12144649 |
It is part of: | Journal of Clinical Medicine, 2023, vol. 12, num. 14 |
URI: | http://hdl.handle.net/2445/204165 |
Related resource: | https://doi.org/10.3390/jcm12144649 |
ISSN: | 2077-0383 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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