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http://hdl.handle.net/2445/207574| Title: | Cognitive and Emotional Symptoms Induced by Chronic Stress Are Regulated by EGR1 in a Subpopulation of Hippocampal Pyramidal Neurons. |
| Author: | Sancho Balsells, Anna Borràs Pernas, Sara Brito, Verónica Alberch i Vié, Jordi Girault, Jean-Antoine Giralt Torroella, Albert |
| Keywords: | Hipocamp (Cervell) Neurones Memòria Esquizofrènia Depressió psíquica Estrès (Psicologia) Hippocampus (Brain) Neurons Memory Schizophrenia Mental depression Stress (Psychology) |
| Issue Date: | 14-Feb-2023 |
| Publisher: | MDPI |
| Abstract: | We found that specific manipulation of superficial but not deep pyramidal neurons of the CA1 resulted in the amelioration of depressive-like behaviors and the restoration of cognitive impairments induced by chronic stress. In summary, Egr1 might be a core molecule driving the activation/deactivation of hippocampal neuronal subpopulations underlying stress-induced alterations involving emotional and cognitive sequels. |
| Note: | Reproducció del document publicat a: https://doi.org/10.3390/ijms24043833 |
| It is part of: | International Journal of Molecular Sciences, 2023, vol. 24, num.4 |
| URI: | http://hdl.handle.net/2445/207574 |
| Related resource: | https://doi.org/10.3390/ijms24043833 |
| DOI: | 10.3390/ijms24043833 |
| ISSN: | 1661-6596 |
| Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Biomedicina) |
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