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http://hdl.handle.net/2445/21371
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DC Field | Value | Language |
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dc.contributor.author | Duque, María D. | cat |
dc.contributor.author | Torres Costa, Eva | cat |
dc.contributor.author | Valverde Murillo, Elena | cat |
dc.contributor.author | Barniol-Xicota, Marta | cat |
dc.contributor.author | Guardiola Bagán, Salvador | cat |
dc.contributor.author | Rey Carrizo, Matías | cat |
dc.contributor.author | Vázquez Cruz, Santiago | cat |
dc.date.accessioned | 2012-01-09T10:46:58Z | - |
dc.date.available | 2012-01-09T10:46:58Z | - |
dc.date.issued | 2011 | - |
dc.identifier.uri | http://hdl.handle.net/2445/21371 | - |
dc.description | Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32392 | - |
dc.description.abstract | Influenza is a highly contagious, major respiratory tract disease affecting millions of people each year. At present, two classes of antivirals are available: the neuraminidase inhibitors and the M2 proton channel blockers amantadine and rimantadine. However, rapid emergence of M2 blockers resistance makes imperative the development of new anti-influenza drugs. In the last few years several groups have synthesized and evaluated several analogs of amantadine. While several of them are active against wild-type M2 channel only a few are able to inhibit the mutant ion channels that lead to amantadine-resistance. | eng |
dc.format.extent | 30 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | eng |
dc.publisher | Transworld Research Network | eng |
dc.relation.isformatof | Reproducció del capítol 2 del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=106 | cat |
dc.relation.ispartof | Recent Advances in Pharmaceutical Sciences, 2011, Chapter 2, p. 35-64. Editor: Diego Muñoz-Torrero | - |
dc.relation.uri | http://hdl.handle.net/2445/32392 | - |
dc.rights | (c) Transworld Research Network, 2011 | - |
dc.source | Llibres / Capítols de llibre (Farmacologia, Toxicologia i Química Terapèutica) | - |
dc.subject.classification | Influenzavirus | cat |
dc.subject.classification | Resistència als medicaments | cat |
dc.subject.classification | Inhibidors enzimàtics | cat |
dc.subject.other | Influenza viruses | eng |
dc.subject.other | Drug resistance | eng |
dc.subject.other | Enzyme inhibitors | eng |
dc.title | Inhibitors of the M2 channel of influenza A virus | eng |
dc.type | info:eu-repo/semantics/bookPart | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 257179 | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Llibres / Capítols de llibre (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
File | Description | Size | Format | |
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257179.pdf | 477.67 kB | Adobe PDF | View/Open |
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