Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/22459
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cervera i Segura, Ricard, 1960- | cat |
dc.contributor.author | Navarro López, Margarita | cat |
dc.contributor.author | López-Soto, Alfonso | cat |
dc.contributor.author | Cid Xutglà, M. Cinta | cat |
dc.contributor.author | Font Franco, Josep, 1953-2006 | cat |
dc.contributor.author | Esparza Sánchez, Jordi | cat |
dc.contributor.author | Reverter Calatayud, Juan Carlos | cat |
dc.contributor.author | Monteagudo Terres, Juan | cat |
dc.contributor.author | Ingelmo Morín, Miguel | cat |
dc.contributor.author | Urbano Márquez, A. (Álvaro) | cat |
dc.date.accessioned | 2012-03-05T12:52:14Z | - |
dc.date.available | 2012-03-05T12:52:14Z | - |
dc.date.issued | 1994 | - |
dc.identifier.issn | 0003-4967 | - |
dc.identifier.uri | http://hdl.handle.net/2445/22459 | - |
dc.description.abstract | OBJECTIVES--To investigate the prevalence and characteristics of antibodies to endothelial cells (aEC) from large vessel and from microvasculature in a group of patients with Behçet's disease (BD) to determine the relationship of these antibodies with clinical and laboratory features of the disease. METHODS--Thirty patients with BD were prospectively and consecutively studied. The aEC were determined by enzyme-linked immunosorbent assay (ELISA) using endothelial cells derived from human umbilical vein (large vessel) as well as from retroperitoneal adipose tissue (microvasculature). RESULTS--Fifteen patients (50%) had aEC, either directed to large vessel [8(26%) patients] or microvascular [13(43%) patients] endothelial cells. The percentage of active patients was significantly higher in the aEC-positive group [12(80%) patients] compared with the aEC-negative group [5(33%) patients] (p < 0.05). CONCLUSIONS--Patients with BD have a high prevalence of aEC when microvascular endothelial cells are used in the assay. These antibodies seem to be a marker of disease activity in this condition, previously considered as negative for autoantibodies. | - |
dc.format.extent | 3 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | eng |
dc.publisher | BMJ Group | - |
dc.relation.isformatof | Reproducció digital del document publicat a: http://dx.doi.org/10.1136/ard.53.4.265 | - |
dc.relation.ispartof | Annals of the Rheumatic Diseases, 1994, vol. 53, núm. 4, p. 265-267 | - |
dc.relation.uri | http://dx.doi.org/10.1136/ard.53.4.265 | - |
dc.rights | (c) BMJ Publishing Group Ltd, 1994 | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Malaltia de Behçet | cat |
dc.subject.classification | Endoteli | cat |
dc.subject.classification | Autoanticossos | cat |
dc.subject.classification | Immunoglobulines | cat |
dc.subject.other | Behçet's disease | eng |
dc.subject.other | Endothelium | eng |
dc.subject.other | Autoantibodies | eng |
dc.subject.other | Immunoglobulins | eng |
dc.title | Antibodies to endothelial cells in Behçet's disease: cell-binding heterogeneity and association with clinical activity | eng |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 101197 | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 8203957 | - |
dc.identifier.pmid | 25774787 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
101197.pdf | 584.16 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.