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Laser-induced forward transfer of liquids: Study of the droplet ejection process

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Laser-induced forward transfer (LIFT) is a laser direct-write technique that offers the possibility of printing patterns with a high spatial resolution from a wide range of materials in a solid or liquid state, such as conductors, dielectrics, and biomolecules in solution. This versatility has made LIFT a very promising alternative to lithography-based processes for the rapid prototyping of biomolecule microarrays. Here, we study the transfer process through the LIFT of droplets of a solution suitable for microarray preparation. The laser pulse energy and beam size were systematically varied, and the effect on the transferred droplets was evaluated. Controlled transfers in which the deposited droplets displayed optimal features could be obtained by varying these parameters. In addition, the transferred droplet volume displayed a linear dependence on the laser pulse energy. This dependence allowed determining a threshold energy density value, independent of the laser focusing conditions, which acted as necessary conditions for the transfer to occur. The corresponding sufficient condition was given by a different total energy threshold for each laser beam dimension. The threshold energy density was found to be the dimensional parameter that determined the amount of the transferred liquid per laser pulse, and there was no substantial loss of material due to liquid vaporization during the transfer.

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COLINA, M., DUOCASTELLA, Martí, FERNÁNDEZ PRADAS, Juan marcos, SERRA COROMINA, Pere, MORENZA GIL, José luis. Laser-induced forward transfer of liquids: Study of the droplet ejection process. _Journal of Applied Physics_. 2006. Vol. 99, núm. 8, pàgs. 084909-1-084909-7. [consulta: 6 de gener de 2026]. ISSN: 0021-8979. [Disponible a: https://hdl.handle.net/2445/24889]

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