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Issue DateTitleAuthor(s)
12-Feb-20141,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studiesDi Pietro, O.; Viayna, Elisabet; Vicente García, Esther; Bartolini, Manuela; Ramón, Rosario; Juárez-Jiménez, Jordi; Clos, Victòria; Pérez Fernández, Belén; Andrisano, Vincenza; Luque Garriga, F. Xavier; Lavilla Grífols, Rodolfo; Muñoz-Torrero López-Ibarra, Diego
27-Mar-2014Synthesis and multi-target biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agentsViayna, Elisabet; Sola, Irene; Bartolini, Manuela; De Simone, Angela; Tapia-Rojas, Cheril; Serrano, Felipe G.; Sabaté Lagunas, Raimon; Juárez-Jiménez, Jordi; Pérez Fernández, Belén; Luque Garriga, F. Xavier; Andrisano, Vincenza; Clos, Victòria; Inestrosa, Nibaldo C.; Muñoz-Torrero López-Ibarra, Diego
12-Sep-2014Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting beta-amyloid, tau, and cholinesterase pathologiesDi Pietro, O.; Pérez Areales, Francisco Javier; Juárez-Jiménez, Jordi; Espargaró Colomé, Alba; Clos, Victòria; Pérez Fernández, Belén; Lavilla Grífols, Rodolfo; Sabaté Lagunas, Raimon; Luque Garriga, F. Xavier; Muñoz-Torrero López-Ibarra, Diego
15-Jan-2020Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin AJuárez-Jiménez, Jordi; Gupta, Arun A.; Karunanithy, Gogulan; Mey, Antonia S. J. S.; Georgiou, Charis; Ioannidis, Harris; De Simone, Alessio; Barlow, Paul N.; Hulme, Alison N.; Walkinshaw, Malcolm D.; Baldwin, Andrew J.; Michel, Julien
23-Oct-2018A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitorsDe Simone, Alessio; Georgiou, Charis; Ioannidis, Harris; Gupta, Arun A.; Juárez-Jiménez, Jordi; Doughty-Shenton, Dahlia; Blackburn, Elizabeth A.; Wear, Martin A.; Richards, Jonathan P.; Barlow, Paul N.; Carragher, Neil; Walkinshaw, Malcolm D.; Hulme, Alison N.; Michel, Julien