Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/32186
Title: Role of JNK in neurodegenerative diseases
Author: Junyent Herena, Fèlix
Verdaguer Cardona, Ester
Folch López, Jaume
Beas Zárate, Carlos
Pallàs i Llibería, Mercè, 1964-
Auladell i Costa, M. Carme
Camins Espuny, Antoni
Keywords: Farmacologia
Malalties neurodegeneratives
Pharmacology
Neurodegenerative Diseases
Issue Date: 2012
Publisher: Transworld Research Network
Abstract: The c-Jun N-terminal kinases (JNK) are members of the MAPK family and can be activated by different stimuli such as cellular stress, heat shock and ultra-violet irradiation. JNKs have different physiological functions and they have been linked to apoptosis in different cell types. Therefore, the JNK signalling pathway is an important target to prevent cell death. In the present chapter, the role of JNKs in neurodegenerative diseases will be discussed, as well as the pharmacological compounds that inhibit this signalling pathway as therapeutic intervention to prevent neuronal death.
Note: Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393
Note: Reproducció del capítol 2 del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=131
It is part of: Recent Advances in Pharmaceutical Sciences II, 2012, Editor: Diego Muñoz-Torrero, Diego Haro and Joan Vallès, Chapter 2, p. 15-28.
Related resource: http://hdl.handle.net/2445/32393
URI: http://hdl.handle.net/2445/32186
Appears in Collections:Llibres / Capítols de llibre (Biologia Cel·lular, Fisiologia i Immunologia)
Llibres / Capítols de llibre (Farmacologia, Toxicologia i Química Terapèutica)

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