Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/32701
Title: Unique features of odorant-binding proteins of the parasitoid wasp Nasonia vitripennis revealed by genome annotation and comparative analyses
Author: Vieira, Filipe G.
Fôret, S.
He, X.
Rozas Liras, Julio A.
Field, L. M.
Zhou, J.-J.
Keywords: Insectes
Olfacte
Proteïnes
Mosquits
Insects
Smell
Proteins
Mosquitoes
Issue Date: Aug-2012
Publisher: Public Library of Science (PLoS)
Abstract: Insects are the most diverse group of animals on the planet, comprising over 90% of all metazoan life forms, and have adapted to a wide diversity of ecosystems in nearly all environments. They have evolved highly sensitive chemical senses that are central to their interaction with their environment and to communication between individuals. Understanding the molecular bases of insect olfaction is therefore of great importance from both a basic and applied perspective. Odorant binding proteins (OBPs) are some of most abundant proteins found in insect olfactory organs, where they are the first component of the olfactory transduction cascade, carrying odorant molecules to the olfactory receptors. We carried out a search for OBPs in the genome of the parasitoid wasp Nasonia vitripennis and identified 90 sequences encoding putative OBPs. This is the largest OBP family so far reported in insects. We report unique features of the N. vitripennis OBPs, including the presence and evolutionary origin of a new subfamily of double-domain OBPs (consisting of two concatenated OBP domains), the loss of conserved cysteine residues and the expression of pseudogenes. This study also demonstrates the extremely dynamic evolution of the insect OBP family: (i) the number of different OBPs can vary greatly between species; (ii) the sequences are highly diverse, sometimes as a result of positive selection pressure with even the canonical cysteines being lost; (iii) new lineage specific domain arrangements can arise, such as the double domain OBP subfamily of wasps and mosquitoes.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0043034
It is part of: PLoS One, 2012, vol. 7, num. 8, p. e43034-e43034
Related resource: http://dx.doi.org/10.1371/journal.pone.0043034
URI: http://hdl.handle.net/2445/32701
ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (Genètica, Microbiologia i Estadística)

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