Please use this identifier to cite or link to this item:
Title: Respiratory chain dysfunction associated with multiple mitochondrial DNA deletions in antiretroviral therapy-related lipodystrophy.
Author: Miró, Òscar
Gómez, Montserrat
Pedrol, Enric
Cardellach, Francesc
Nunes Martínez, Virginia
Casademont i Pou, Jordi
Keywords: Antiretrovirals
Infeccions per VIH
Antiretroviral agents
HIV infections
Issue Date: 18-Aug-2000
Publisher: Lippincott Williams & Wilkins
Abstract: Highly-active antiretroviral therapy (HAART) can induce a characteristic lipodystrophy syndrome characterized by peripheral fat wasting and central adiposity, usually associated with hyperlipidaemia and insulin resistance [1,2]. Indirect data have led some authors to propose that mitochondrial dysfunction could play a role in this syndrome [3,4].To date, as recently outlined by Kakuda et al. [5] in this journal, HIV-infected patients developing lipodystrophy have not been studied for mitochondrial changes or respiratory chain capacity...
Note: Versió postprint del document publicat a:
It is part of: AIDS, 2000, vol. 14, num. 12, p. 1855-1857
ISSN: 0269-9370
Appears in Collections:Articles publicats en revistes (Ciències Fisiològiques)
Articles publicats en revistes (Medicina)

Files in This Item:
File Description SizeFormat 
157892.pdf279.52 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.