Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/42863
Title: Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
Author: Rodríguez García, M.
Climent, N.
Oliva, H.
Casanova, V.
Franco Fernández, Rafael
Leon, A.
Gatell, José M.
García, F.
Gallart, T.
Keywords: VIH (Virus)
Immunologia
HIV (Viruses)
Immunology
Issue Date: 2010
Publisher: Public Library of Science (PLoS)
Abstract: Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction plays a critical role during the first steps of HIV infection, we investigated the possible impact of α-defensins1-3 production by DC on disease progression.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0009436
It is part of: PLoS One, 2010, vol. 5, num. 2, p. e9436-e9436
Related resource: http://dx.doi.org/10.1371/journal.pone.0009436
URI: http://hdl.handle.net/2445/42863
ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (Bioquímica i Biomedicina Molecular)
Articles publicats en revistes (Medicina)

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