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|Title:||Perspectives for the treatment of brucellosis in the 21st century: the Ioannina recommendations.|
|Author:||Ariza Cardenal, Javier|
Colmenero, Juan D.
Corbel, Michael J.
Falagas, Matthew E.
Memish, Ziad A.
Roushan, Mohammad Reza Hansanjani
Sipsas, Nikolaos V.
Young, Edward J.
|Publisher:||Public Library of Science (PLoS)|
|Abstract:||Brucellosis is probably the commonest anthropozoonotic infection worldwide [1-3], but remains in various aspects an enigma in the 21st century . Brucella melitensis remains the major cause of human disease worldwide, followed by B. abortus and B. suis, while rare but persisting cases of B. canis human infection and disease by novel Brucella pathogens of marine mammals have also emerged. The disease is re-emerging as a significant cause of travel-related disease  and represents an index of poor socioeconomic status (Figure 1). Its treatment is largely based even today on the principles applied half a century ago by pioneer researchers  and few modifications have been made in the following years, despite the emergence of new antibiotic classes and different therapeutic approaches .|
|Note:||Reproducció del document publicat a: 10.1371/journal.pmed.0040317|
|It is part of:||PLoS Medicine, 2007, vol. 4, num. 12, p. 1872-1878|
|Appears in Collections:||Articles publicats en revistes (Ciències Clíniques)|
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