Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/44003
Title: Genetically-defined deficiency of mannose-binding lectin is associated with protection after experimental stroke in mice and outcome in human stroke
Author: Cervera Álvarez, Álvaro
Planas Obradors, Anna Maria
Justicia Mercader, Carles
Urra, Xabier
Jensenius, Jens C.
Torres Peraza, Jesús Fernando
Lozano Soto, Francisco
Chamorro Sánchez, Ángel
Keywords: Enzims proteolítics
Infart cerebral
Immunitat
Models animals en la investigació
Proteolytic enzymes
Cerebral infarctio
Immunity
Animal models in research
Issue Date: Feb-2010
Publisher: Public Library of Science (PLoS)
Abstract: The complement system is a major effector of innate immunity that has been involved in stroke brain damage. Complement activation occurs through the classical, alternative and lectin pathways. The latter is initiated by mannose-binding lectin (MBL) and MBL-associated serine proteases (MASPs). Here we investigated whether the lectin pathway contributes to stroke outcome in mice and humans.
Note: Reproducció del document publicat a: 10.1371/journal.pone.0008433
It is part of: PLoS One, 2010, vol. 5, num. 2, p. e8433
Related resource: http://dx.doi.org/10.1371/journal.pone.0008433
URI: http://hdl.handle.net/2445/44003
ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (Biomedicina)

Files in This Item:
File Description SizeFormat 
598553.pdf448.14 kBAdobe PDFView/Open


This item is licensed under a Creative Commons License Creative Commons