Solid-phase synthesis and DNA binding studies of dichloroplatinum(II) conjugates of dicarba analogues of octreotide as a new anticancer drugs

Barragán, Flavia; Moreno Martínez, Virtudes; Marchán Sancho, Vicente

Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/44244

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DC Field	Value	Language
dc.contributor.author	Barragán, Flavia	-
dc.contributor.author	Moreno Martínez, Virtudes	-
dc.contributor.author	Marchán Sancho, Vicente	-
dc.date.accessioned	2013-06-14T07:50:44Z	-
dc.date.available	2013-06-14T07:50:44Z	-
dc.date.issued	2009	-
dc.identifier.issn	1359-7345	-
dc.identifier.uri	http://hdl.handle.net/2445/44244	-
dc.description.abstract	The first dichloroplatinum(II) conjugates of dicarba analogues of octreotide , which is expected to act as a"tumour-targeting device", have been efficiently synthesized following a stepwise solid-phase approach; these compounds emulate the mechanism of cisplatin since they form a 1,2-intrastrand cross-link with two consecutive guanines of an oligonucleotide.	-
dc.format.extent	3 p.	-
dc.format.mimetype	application/pdf	-
dc.language.iso	eng	-
dc.publisher	Royal Society of Chemistry	-
dc.relation.isformatof	Versió postprint del document publicat a: http://dx.doi.org/10.1039/B909698A	-
dc.relation.ispartof	Chemical Communications, 2009, p. 4705-4707	-
dc.relation.uri	http://dx.doi.org/10.1039/B909698A	-
dc.rights	(c) Barragán, Flavia et al., 2009	-
dc.source	Articles publicats en revistes (Química Inorgànica i Orgànica)	-
dc.subject.classification	ADN	-
dc.subject.classification	Química bioinorgànica	-
dc.subject.classification	Quimioteràpia del càncer	-
dc.subject.classification	Cèl·lules canceroses	-
dc.subject.classification	Toxicitat dels medicaments	-
dc.subject.other	DNA	-
dc.subject.other	Bioinorganic chemistry	-
dc.subject.other	Cancer chemotherapy	-
dc.subject.other	Cancer cells	-
dc.subject.other	Drug toxicity	-
dc.title	Solid-phase synthesis and DNA binding studies of dichloroplatinum(II) conjugates of dicarba analogues of octreotide as a new anticancer drugs	-
dc.type	info:eu-repo/semantics/article	-
dc.type	info:eu-repo/semantics/acceptedVersion	-
dc.identifier.idgrec	568522	-
dc.date.updated	2013-06-14T07:50:44Z	-
dc.rights.accessRights	info:eu-repo/semantics/openAccess	-
Appears in Collections:	Articles publicats en revistes (Química Inorgànica i Orgànica)

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