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http://hdl.handle.net/2445/46583
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DC Field | Value | Language |
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dc.contributor.author | Sala Vila, Aleix | - |
dc.contributor.author | Harris, William S. | - |
dc.contributor.author | Cofán Pujol, Montserrat | - |
dc.contributor.author | Pérez-Heras, Ana Maria | - |
dc.contributor.author | Pintó Sala, Xavier | - |
dc.contributor.author | Lamuela Raventós, Rosa Ma. | - |
dc.contributor.author | Covas Planells, María Isabel | - |
dc.contributor.author | Estruch Riba, Ramon | - |
dc.contributor.author | Ros Rahola, Emilio | - |
dc.date.accessioned | 2013-10-01T15:52:19Z | - |
dc.date.available | 2013-10-01T15:52:19Z | - |
dc.date.issued | 2011-08 | - |
dc.identifier.issn | 0007-1145 | - |
dc.identifier.uri | http://hdl.handle.net/2445/46583 | - |
dc.description.abstract | The omega-3 index, defined as the sum of EPA and DHA in erythrocyte membranes expressed as a percentage of total fatty acids, has been proposed as both a risk marker and risk factor for CHD death. A major determinant of the omega-3 index is EPA þ DHA intake, but the impact of other dietary fatty acids has not been investigated. In a cross-sectional study on 198 subjects (102 men and 96 women, mean age 66 years) at high cardiovascular risk living in Spain, the country with low rates of cardiac death despite a high prevalence of cardiovascular risk factors, dietary data were acquired from FFQ and blood cell membrane fatty acid composition was measured by GC. The average consumption of EPA þ DHA was 0·9 g/d and the mean omega-3 index was 7·1%. In multivariate models, EPA þ DHA intake was the main predictor of the omega-3 index but explained only 12% of its variability (P,0·001). No associations with other dietary fatty acids were observed. Although the single most influential determinant of the omega-3 index measured here was the intake of EPA þ DHA, it explained little of the former"s variability; hence, the effects of other factors (genetic, dietary and lifestyle) remain to be determined. Nevertheless, the high omega-3 index could at least partially explain the paradox of low rates of fatal CHD in Spain despite a high background prevalence of cardiovascular risk factors. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Cambridge University Press | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.1017/S0007114511000171 | - |
dc.relation.ispartof | British Journal of Nutrition, 2011, vol. 106, num. 3, p. 425-431 | - |
dc.relation.uri | http://dx.doi.org/10.1017/S0007114511000171 | - |
dc.rights | (c) Cambridge University Press, 2011 | - |
dc.source | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) | - |
dc.subject.classification | Dieta | - |
dc.subject.classification | Malalties cardiovasculars | - |
dc.subject.classification | Factors de risc en les malalties | - |
dc.subject.classification | Àcids grassos omega-3 | - |
dc.subject.other | Diet | - |
dc.subject.other | Cardiovascular diseases | - |
dc.subject.other | Risk factors in diseases | - |
dc.subject.other | Omega-3 fatty acids | - |
dc.title | Determinants of the omega-3 index in a Mediterranean population at increased risk for CHD. | eng |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 601196 | - |
dc.date.updated | 2013-10-01T15:52:19Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 21450116 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) Articles publicats en revistes (Podologia) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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File | Description | Size | Format | |
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601196.pdf | 126.35 kB | Adobe PDF | View/Open |
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