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http://hdl.handle.net/2445/46884
Title: | Critical Behavior and Axis Defining Symmetry Breaking in Hydra Embryonic Development |
Author: | Gamba, Andrea Nicodemi, Mario Soriano i Fradera, Jordi Ott, Albrecht |
Keywords: | Hidrozous Biofísica Embriologia Regeneració (Biologia) Cèl·lules Càncer Hydrozoa Biophysics Embryology Regeneration (Biology) Cells Cancer |
Issue Date: | 2012 |
Publisher: | American Physical Society |
Abstract: | The formation of a hollow cellular sphere is often one of the first steps of multicellular embryonic development. In the case of Hydra, the sphere breaks its initial symmetry to form a foot-head axis. During this process a gene, ks1, is increasingly expressed in localized cell domains whose size distribution becomes scale-free at the axis-locking moment. We show that a physical model based solely on the production and exchange of ks1-promoting factors among neighboring cells robustly reproduces the scaling behavior as well as the experimentally observed spontaneous and temperature-directed symmetry breaking. |
Note: | Reproducció del document publicat a: http://dx.doi.org/ 10.1103/PhysRevLett.108.158103 |
It is part of: | Physical Review Letters, 2012, vol. 108, num. 15, p. 158103-1-158103-5 |
URI: | http://hdl.handle.net/2445/46884 |
Related resource: | http://dx.doi.org/10.1103/PhysRevLett.108.158103 |
ISSN: | 0031-9007 |
Appears in Collections: | Articles publicats en revistes (Física Quàntica i Astrofísica) |
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617480.pdf | 451.62 kB | Adobe PDF | View/Open |
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