Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/48630
Title: Preparation of alpha-labeled aldehydes by base-catalyzed exchange reactions
Author: Ariza Piquer, Xavier
Asins Muñoz, Guillermina
García Gómez, Jordi
García Hegardt, Fausto
Makowski, Kamil
Serra i Cucurull, Dolors
Velasco Turbau, Javier
Keywords: Trastorns del metabolisme dels lípids
Bioquímica
Aldehids
Disseny de medicaments
Medicina nuclear
Lipid metabolism disorders
Biochemistry
Aldehydes
Drug design
Nuclear medicine
Issue Date: 2010
Publisher: John Wiley & Sons
Abstract: A simple, efficient protocol for the preparation of α-labeled aldehydes based on H/D exchange catalyzed by 4-(N,N-dimethylamino)pyridine or Et3N is described. High chemical yields and ratios of isotope incorporation were obtained even when small amounts (1 mmol) of aldehyde were used.
Note: Versió preprint del document publicat a: http://dx.doi.org/10.1002/jlcr.1759
It is part of: Journal of Labelled Compounds and Radiopharmaceuticals, 2010, vol. 53, num. 8, p. 556-558
Related resource: http://dx.doi.org/10.1002/jlcr.1759
URI: http://hdl.handle.net/2445/48630
ISSN: 0362-4803
Appears in Collections:Articles publicats en revistes (Química Inorgànica i Orgànica)
Articles publicats en revistes (Bioquímica i Biomedicina Molecular)

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