Please use this identifier to cite or link to this item:
Title: Are bipolar II patients cognitively impaired? A systematic review
Author: Solé, Brisa
Martínez-Arán, Anabel, 1971-
Torrent, C.
Bonnín, Caterina del Mar
Reinares, Maria
Popovic, D.
Sánchez-Moreno, José
Vieta i Pascual, Eduard, 1963-
Keywords: Trastorn bipolar
Trastorns de la cognició
Manic-depressive illness
Cognition disorders
Issue Date: 28-Jan-2011
Publisher: Cambridge University Press
Abstract: BACKGROUND: There is evidence that bipolar disorder (BD) is associated with significant neurocognitive deficits and this occurs in individuals with BD type I (BD I) and with BD type II (BD II). Only a few studies have focused on cognitive impairment in BD II. The aim of this study was to describe the pattern of cognitive impairment in patients with BD II, in order to identify specific cognitive deficits that distinguish BD II from BD I patients as well as from healthy subjects. METHOD: We performed a systematic review of the literature of neuropsychological studies of BD II published between 1980 and July 2009. Fourteen articles fulfilled the inclusion criteria and were included in this review. RESULTS: Main cognitive deficits found in BD II include working memory and some measures of executive functions (inhibitory control) and approximately half of the studies also detected verbal memory impairment. CONCLUSIONS: There are subtle differences between the two subtypes regarding cognition. This may suggest neurobiological differences between the two subgroups which will be helpful in order to determine cognitive endophenotypes in BD subtypes.
Note: Reproducció del document publicat a:
It is part of: Psychological Medicine, 2011, vol. 41, p. 1791-1803
Related resource:
ISSN: 0033-2917
Appears in Collections:Articles publicats en revistes (Psicologia Clínica i Psicobiologia)

Files in This Item:
File Description SizeFormat 
587142.pdf103.92 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.