Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/52283
Title: Are bipolar II patients cognitively impaired? A systematic review
Author: Solé, B.
Martínez-Arán, Anabel, 1971-
Torrent, C.
Bonnín Roig, Caterina del Mar
Reinares, M.
Popovic, D.
Sánchez-Moreno, José
Vieta i Pascual, Eduard, 1963-
Keywords: Trastorn bipolar
Neuropsicologia
Trastorns de la cognició
Manic-depressive illness
Neuropsychology
Cognition disorders
Issue Date: 28-Jan-2011
Publisher: Cambridge University Press
Abstract: BACKGROUND: There is evidence that bipolar disorder (BD) is associated with significant neurocognitive deficits and this occurs in individuals with BD type I (BD I) and with BD type II (BD II). Only a few studies have focused on cognitive impairment in BD II. The aim of this study was to describe the pattern of cognitive impairment in patients with BD II, in order to identify specific cognitive deficits that distinguish BD II from BD I patients as well as from healthy subjects. METHOD: We performed a systematic review of the literature of neuropsychological studies of BD II published between 1980 and July 2009. Fourteen articles fulfilled the inclusion criteria and were included in this review. RESULTS: Main cognitive deficits found in BD II include working memory and some measures of executive functions (inhibitory control) and approximately half of the studies also detected verbal memory impairment. CONCLUSIONS: There are subtle differences between the two subtypes regarding cognition. This may suggest neurobiological differences between the two subgroups which will be helpful in order to determine cognitive endophenotypes in BD subtypes.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1017/S0033291711000018
It is part of: Psychological Medicine, 2011, vol. 41, p. 1791-1803
Related resource: http://dx.doi.org/10.1017/S0033291711000018
URI: http://hdl.handle.net/2445/52283
ISSN: 0033-2917
Appears in Collections:Articles publicats en revistes (Psicologia Clínica i Psicobiologia)

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