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http://hdl.handle.net/2445/53332
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DC Field | Value | Language |
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dc.contributor.author | Saurí Duran, Jaume | - |
dc.contributor.author | Millán, D. | - |
dc.contributor.author | Suñé i Negre, Josep M. (Josep Maria) | - |
dc.contributor.author | Pérez Lozano, Pilar | - |
dc.contributor.author | Sarrate Arjona, Rocio | - |
dc.contributor.author | Fábregas, A. (Anna) | - |
dc.contributor.author | Carrillo Sánchez, Carolina | - |
dc.contributor.author | Miñarro Carmona, Montserrat | - |
dc.contributor.author | Ticó Grau, Josep R. | - |
dc.contributor.author | García Montoya, Encarna | - |
dc.date.accessioned | 2014-04-08T09:05:35Z | - |
dc.date.available | 2014-04-08T09:05:35Z | - |
dc.date.issued | 2014-01-30 | - |
dc.identifier.issn | 0378-5173 | - |
dc.identifier.uri | http://hdl.handle.net/2445/53332 | - |
dc.description.abstract | The SeDeM Diagram Expert System has been used to study excipients, Captopril and designed formulations for their galenic characterization and to ascertain the critical points of the formula affecting product quality to obtain suitable formulations of Captopril Direct Compression SR Matrix Tablets. The application of the Sedem Diagram Expert System enables selecting excipients with in order to optimize the formula in the preformulation and formulation studies. The methodology is based on the implementation of ICH Q8, establishing the design space of the formula with the use of experiment design, using the parameters of the SeDeM Diagram Expert System as system responses. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier B.V. | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.1016/j.ijpharm.2013.11.029 | - |
dc.relation.ispartof | International Journal of Pharmaceutics, 2014, vol. 461, num. 1-2, p. 38-45 | - |
dc.relation.uri | http://dx.doi.org/10.1016/j.ijpharm.2013.11.029 | - |
dc.rights | (c) Elsevier B.V., 2014 | - |
dc.source | Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) | - |
dc.subject.classification | Comprimits (Medicina) | - |
dc.subject.classification | Medicació oral | - |
dc.subject.classification | Excipients | - |
dc.subject.classification | Control de qualitat | - |
dc.subject.classification | Medicaments d'alliberament retardat | - |
dc.subject.classification | Tecnologia farmacèutica | - |
dc.subject.classification | Pólvores (Farmàcia) | - |
dc.subject.other | Tablets (Medicine) | - |
dc.subject.other | Oral medication | - |
dc.subject.other | Excipients | - |
dc.subject.other | Quality control | - |
dc.subject.other | Delayed-action drugs | - |
dc.subject.other | Pharmaceutical technology | - |
dc.subject.other | Powders (Pharmacy) | - |
dc.title | The use of the SeDeM diagram expert system for the formulation of Captopril SR matrix tablets by direct compression | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 630651 | - |
dc.date.updated | 2014-04-08T09:05:36Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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630651.pdf | 1.69 MB | Adobe PDF | View/Open |
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