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Title: Executive dysfunction and memory impairment in schizoaffective disorder: a comparison with bipolar disorder, schizophrenia and healthy controls.
Author: Amann, Benedikt
Gomar, J. J.
Ortiz Gil, Jordi
McKenna, P.
Sans-Sansa, B.
Sarró, S.
Moro, N.
Madre, M.
Landin-Romero, R.
Vieta i Pascual, Eduard, 1963-
Goikolea, José Manuel
Salvador, R.
Pomarol-Clotet, Edith
Keywords: Esquizofrènia
Trastorn bipolar
Manic-depressive illness
Issue Date: 23-Feb-2012
Publisher: Cambridge University Press
Abstract: BACKGROUND: Deficits in memory and executive performance are well-established features of bipolar disorder and schizophrenia. By contrast, data on cognitive impairment in schizoaffective disorder are scarce and the findings are conflicting. METHOD: We used the Wechsler Memory Scale (WMS-III) and the Behavioural Assessment of the Dysexecutive Syndrome (BADS) to test memory and executive function in 45 schizophrenic patients, 26 schizomanic patients and 51 manic bipolar patients in comparison to 65 healthy controls. The patients were tested when acutely ill. RESULTS: All three patient groups performed significantly more poorly than the controls on global measures of memory and executive functioning, but there were no differences among the patient groups. There were few differences in memory and executive function subtest scores within the patient groups. There were no differences in any test scores between manic patients with and without psychotic symptoms. CONCLUSIONS: Schizophrenic, schizomanic and manic patients show a broadly similar degree of executive and memory deficits in the acute phase of illness. Our results do not support a categorical differentiation across different psychotic categories with regard to neuropsychological deficits.
Note: Reproducció del document publicat a:
It is part of: Psychological Medicine, 2012, vol. 42, p. 2127-2135
Related resource:
ISSN: 0033-2917
Appears in Collections:Articles publicats en revistes (Psicologia Clínica i Psicobiologia)

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