Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/54973
Full metadata record
DC FieldValueLanguage
dc.contributor.authorRuiz España, Neus-
dc.contributor.authorMontero Barrientos, Ma. Teresa-
dc.contributor.authorBorrell Hernández, Jordi-
dc.contributor.authorViñas, Miquel-
dc.date.accessioned2014-06-13T09:34:14Z-
dc.date.available2014-06-13T09:34:14Z-
dc.date.issued2003-08-
dc.identifier.issn1076-6294-
dc.identifier.urihttp://hdl.handle.net/2445/54973-
dc.description.abstractThe outer membrane permeability of Serratia marcescens was studied by comparing porin-deficient mutants with their parental strains. Omp1-deficient strains were selected by moxalactam resistance, whereas mutants lacking the Omp2 porin were obtained by experimental infection with the SMP2 phage, whose primary receptor is the Omp2 porin. The role of porins was demonstrated in quinolone accumulation assays, where semi-quantitative differences in accumulation were observed. Permeability coefficients to cephaloridine of Omp1 mutants were determined and compared with those of the parental strain. The clinical isolates S. marcescens HCPR1 and 866 showed 30- to 200-fold reduced permeability coefficients when Omp1 porin was absent-
dc.format.extent8 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherMary Ann Liebert, Inc.-
dc.relation.isformatofReproducció del document publicat a: http://dx.doi.org/10.1089/107662903322286463-
dc.relation.ispartofMicrobial Drug Resistance, 2003, vol. 9, num. 3, p. 257-264-
dc.relation.urihttp://dx.doi.org/10.1089/107662903322286463-
dc.rights(c) Mary Ann Liebert, Inc., 2003-
dc.sourceArticles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)-
dc.subject.classificationResistència als medicaments-
dc.subject.classificationAntibiòtics-
dc.subject.classificationMedicaments antibacterianscat
dc.subject.classificationSerratia marcescenscat
dc.subject.otherDrug resistance-
dc.subject.otherAntibiotics-
dc.subject.otherAntibacterial agentseng
dc.subject.otherSerratia marcescenseng
dc.titleThe role of Serratia marcescens porins in antibiotic resistanceeng
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec510659-
dc.date.updated2014-06-13T09:34:14Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Patologia i Terapèutica Experimental)
Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)

Files in This Item:
File Description SizeFormat 
510659.pdf2.25 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.