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http://hdl.handle.net/2445/54973
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DC Field | Value | Language |
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dc.contributor.author | Ruiz España, Neus | - |
dc.contributor.author | Montero Barrientos, Ma. Teresa | - |
dc.contributor.author | Borrell Hernández, Jordi | - |
dc.contributor.author | Viñas, Miquel | - |
dc.date.accessioned | 2014-06-13T09:34:14Z | - |
dc.date.available | 2014-06-13T09:34:14Z | - |
dc.date.issued | 2003-08 | - |
dc.identifier.issn | 1076-6294 | - |
dc.identifier.uri | http://hdl.handle.net/2445/54973 | - |
dc.description.abstract | The outer membrane permeability of Serratia marcescens was studied by comparing porin-deficient mutants with their parental strains. Omp1-deficient strains were selected by moxalactam resistance, whereas mutants lacking the Omp2 porin were obtained by experimental infection with the SMP2 phage, whose primary receptor is the Omp2 porin. The role of porins was demonstrated in quinolone accumulation assays, where semi-quantitative differences in accumulation were observed. Permeability coefficients to cephaloridine of Omp1 mutants were determined and compared with those of the parental strain. The clinical isolates S. marcescens HCPR1 and 866 showed 30- to 200-fold reduced permeability coefficients when Omp1 porin was absent | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Mary Ann Liebert, Inc. | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.1089/107662903322286463 | - |
dc.relation.ispartof | Microbial Drug Resistance, 2003, vol. 9, num. 3, p. 257-264 | - |
dc.relation.uri | http://dx.doi.org/10.1089/107662903322286463 | - |
dc.rights | (c) Mary Ann Liebert, Inc., 2003 | - |
dc.source | Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) | - |
dc.subject.classification | Resistència als medicaments | - |
dc.subject.classification | Antibiòtics | - |
dc.subject.classification | Medicaments antibacterians | cat |
dc.subject.classification | Serratia marcescens | cat |
dc.subject.other | Drug resistance | - |
dc.subject.other | Antibiotics | - |
dc.subject.other | Antibacterial agents | eng |
dc.subject.other | Serratia marcescens | eng |
dc.title | The role of Serratia marcescens porins in antibiotic resistance | eng |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 510659 | - |
dc.date.updated | 2014-06-13T09:34:14Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) |
Files in This Item:
File | Description | Size | Format | |
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510659.pdf | 2.25 MB | Adobe PDF | View/Open |
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