Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/54980
Title: First enantioselective synthesis of isagarin, a natural product isolated from Pentas longiflora Oliv.
Author: Jacobs, Jan
Claessens, Sven
Mol, Eva de
El Hady, Samir
Minguillón Llombart, Cristina
Álvarez Domingo, Mercedes
Kimpe, Norbert de
Keywords: Síntesi asimètrica
Productes naturals
Asymmetric synthesis
Natural products
Issue Date: 30-Apr-2010
Publisher: Elsevier B.V.
Abstract: For the first time, an enantioselective synthesis of both 1R,4S-isagarin 1a and 1S,4R-isagarin 1b was achieved starting from 1,4-dimethoxy-2-vinylnaphtalene 2. The key steps involve a Sharpless asymmetric dihydroxylation and reaction with an acetonylating pyridinium ylid.
Note: Versió postprint del document publicat a: http://dx.doi.org/10.1016/j.tet.2010.04.105
It is part of: Tetrahedron, 2010, vol. 66, num. 27-28, p. 5158-5160
Related resource: http://dx.doi.org/10.1016/j.tet.2010.04.105
URI: http://hdl.handle.net/2445/54980
ISSN: 0040-4020
Appears in Collections:Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

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