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Title: Microstructural Brain Differences Predict Functional Hemodynamic Responses in a Reward Processing Task
Author: Càmara, Estela
Rodríguez Fornells, Antoni
Münte, Thomas F.
Keywords: Cervell
Conducta (Psicologia)
Human behavior
Issue Date: 2010
Publisher: The Society for Neuroscience
Abstract: Many aspects of human behavior are driven by rewards, yet different people are differentially sensitive to rewards and punishment. In this study, we showthat white matter microstructure inthe uncinate/inferiorfronto-occipitalfasciculus, defined byfractional anisotropy values derived from diffusion tensor magnetic resonance images, correlates with both short-term (indexed by the fMRI blood oxygenation level-dependent response to reward in the nucleus accumbens) and long-term (indexed by the trait measure sensitivity to punishment) reactivityto rewards.Moreover,traitmeasures of reward processingwere also correlatedwith reward-relatedfunctional activation in the nucleus accumbens. The white matter tract revealed by the correlational analysis connects the anterior temporal lobe with the medial and lateral orbitofrontal cortex and also supplies the ventral striatum. The pattern of strong correlations suggests an intimate relationship betweenwhitematter structure and reward-related behaviorthatmay also play a rolein a number of pathological conditions, such as addiction and pathological gambling.
Note: Reproducció del document publicat a:;
It is part of: Journal of Neuroscience, 2010, vol. 30, num. 34, p. 11398-11402
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ISSN: 0270-6474
Appears in Collections:Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació)

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