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Title: Non-invasive diagnostic and prognostic evaluation of liver cirrhosis and portal hypertension.
Author: Berzigotti, Annalisa
Ashkenazi, Eyal
Reverter, Enric
González-Abraldes Iglesias, Juan
Bosch i Genover, Jaume
Keywords: Cirrosi hepàtica
Hipertensió portal
Malalties del fetge
Hepatic cirrhosis
Portal hypertension
Liver diseases
Issue Date: 1-Mar-2011
Publisher: IOS Press
Abstract: Cirrhosis is the final stage of most of chronic liver diseases, and is almost invariably complicated by portal hypertension, which is the most important cause of morbidity and mortality in these patients. This review will focus on the non-invasive methods currently used in clinical practice for diagnosing liver cirrhosis and portal hypertension. The first-line techniques include physical examination, laboratory parameters, transient elastography and Doppler-US. More sophisticated imaging methods which are less commonly employed are CT scan and MRI, and new technologies which are currently under evaluation are MR elastography and acoustic radiation force imaging (ARFI). Even if none of them can replace the invasive measurement of hepatic venous pressure gradient and the endoscopic screening of gastroesophageal varices, they notably facilitate the clinical management of patients with cirrhosis and portal hypertension, and provide valuable prognostic information.
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It is part of: Disease Markers, 2011, vol. 31, num. 3, p. 129-138
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ISSN: 0278-0240
Appears in Collections:Articles publicats en revistes (Medicina)

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