Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/59336
Title: Extracorporeal liver support in severe alcoholic hepatitis
Author: Parés Darnaculleta, Albert
Mas, Antoni
Keywords: Alcoholisme
Síndrome hepatorenal
Alcoholism
Hepatorenal syndrome
Issue Date: 7-Jul-2014
Publisher: Baishideng Publishing Group
Abstract: The severity of alcoholic hepatitis (AH) which may coexist with cirrhosis varies greatly, from asymptomatic forms which are detected in alcoholic patients without any sign of liver disease, except laboratory abnormalities, to severe forms characterised by deep jaundice, ascites, hepatic encephalopathy and low prothrombin index. In hospitalized patients the mortality could be as high as 75%. The elevated number of therapeutic proposals reported for more than forty years reveals the lack of efficacy of a particular modality. Even in the most favorable trials, the survival is already very poor and in some cases related to the development of renal failure or hepatorenal syndrome. There are some motivating reports concerning albumin dialysis as a support treatment in patients with severe AH, either alone or in combination with other pharmacological therapies. The favorable effects of albumin dialysis in patients with severe AH suggest that the procedure used alone or in combination with other therapies may have a role in this clinical condition. This will be particularly relevant to offer an alternative therapy in these patients, thus being a potential bridge to recovery or to be listed for liver transplantation.
Note: Reproducció del document publicat a: http://dx.doi.org/10.3748/wjg.v20.i25.8011
It is part of: World Journal of Gastroenterology, 2014, vol. 20, num. 25, p. 8011-8017
Related resource: http://dx.doi.org/10.3748/wjg.v20.i25.8011
URI: http://hdl.handle.net/2445/59336
ISSN: 1007-9327
Appears in Collections:Articles publicats en revistes (Medicina)

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