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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/61086
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dc.contributor.authorAmat Tusón, Mercedes-
dc.contributor.authorKöver, Andrea-
dc.contributor.authorJokic, Danica-
dc.contributor.authorLozano, Oscar-
dc.contributor.authorPérez Bosch, Maria-
dc.contributor.authorLandoni, Nicola-
dc.contributor.authorSubrizi, Fabiana-
dc.contributor.authorBautista, Jesús-
dc.contributor.authorBosch Cartes, Joan-
dc.date.accessioned2015-01-08T18:30:18Z-
dc.date.available2015-01-08T18:30:18Z-
dc.date.issued2010-
dc.identifier.issn1551-7012-
dc.identifier.urihttp://hdl.handle.net/2445/61086-
dc.description.abstractA straightforward synthesis of the Met antagonist JLK1360 involving an alkylationcyclocondensation process using aminothiazole 1 and nitrophenacyl bromide 2, reduction of the nitro group, and coupling of the resulting tetracyclic aniline 5 with an appropriate N-acyl alanine derivative, is reported.-
dc.format.extent7 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherMichigan Publishing-
dc.relation.isformatofReproducció del document publicat a: http://dx.doi.org/10.3998/ark.5550190.0011.313-
dc.relation.ispartofArkivoc, vol. 2010, núm. 3, p. 145-151-
dc.relation.urihttp://dx.doi.org/10.3998/ark.5550190.0011.313-
dc.rightscc-by-nc (c) Amat Tusón, Mercedes et al., 2010-
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/es-
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)-
dc.subject.classificationBioquímica-
dc.subject.classificationAmines-
dc.subject.classificationDianes farmacològiques-
dc.subject.classificationProteïnes quinases-
dc.subject.classificationTransducció de senyal cel·lular-
dc.subject.otherBiochemistry-
dc.subject.otherAmines-
dc.subject.otherDrug targeting-
dc.subject.otherProtein kinases-
dc.subject.otherCellular signal transduction-
dc.titleSynthesis of a tetrahydroimidazo-[2',1':2,3]thiazolo[5,4-c]pyridine derivative with Met inhibitory activity-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec568739-
dc.date.updated2015-01-08T18:30:19Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
Articles publicats en revistes (Institut de Biomedicina (IBUB))

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