Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/61171
Title: | Gram-negative flagella glycosylation |
Author: | Merino Montero, Susana Tomàs Magaña, Juan |
Keywords: | Flagel·lats Bacteris Genètica bacteriana Glicoproteïnes Bacteris patògens Flagellata Bacteria Bacterial genetics Glycoproteins Pathogenic bacteria |
Issue Date: | 19-Feb-2014 |
Publisher: | MDPI |
Abstract: | Protein glycosylation had been considered as an eccentricity of a few bacteria. However, through advances in analytical methods and genome sequencing, it is now established that bacteria possess both N-linked and O-linked glycosylation pathways. Both glycosylation pathways can modify multiple proteins, flagellins from Archaea and Eubacteria being one of these. Flagella O-glycosylation has been demonstrated in many polar flagellins from Gram-negative bacteria and in only the Gram-positive genera Clostridium and Listeria. Furthermore, O-glycosylation has also been demonstrated in a limited number of lateral flagellins. In this work, we revised the current advances in flagellar glycosylation from Gram-negative bacteria, focusing on the structural diversity of glycans, the O-linked pathway and the biological function of flagella glycosylation. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.3390/ijms15022840 |
It is part of: | International Journal of Molecular Sciences, 2014, vol. 15, p. 2840-2857 |
URI: | http://hdl.handle.net/2445/61171 |
Related resource: | http://dx.doi.org/10.3390/ijms15022840 |
ISSN: | 1422-0067 |
Appears in Collections: | Articles publicats en revistes (Genètica, Microbiologia i Estadística) |
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