Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/61173
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Merino Montero, Susana | - |
dc.contributor.author | Wilhelms, Markus | - |
dc.contributor.author | Tomàs Magaña, Juan | - |
dc.date.accessioned | 2015-01-12T15:34:44Z | - |
dc.date.available | 2015-01-12T15:34:44Z | - |
dc.date.issued | 2014-10-28 | - |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | http://hdl.handle.net/2445/61173 | - |
dc.description.abstract | Polar flagellin proteins from Aeromonas hydrophila strain AH-3 (serotype O34) were found to be O-glycosylated with a heterogeneous heptasaccharide glycan. Two mutants with altered (light and strong) polar flagella glycosylation still able to produce flagella were previously obtained, as well as mutants lacking the O34-antigen lipopolysaccharide (LPS) but with unaltered polar flagella glycosylation. We compared these mutants, altogether with the wild type strain, in different studies to conclude that polar flagella glycosylation is extremely important for A. hydrophila adhesion to Hep-2 cells and biofilm formation. Furthermore, the polar flagella glycosylation is an important factor for the immune stimulation of IL-8 production via toll receptor 5 (TLR5). | - |
dc.format.extent | 12 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.3390/ijms151221935 | - |
dc.relation.ispartof | International Journal of Molecular Sciences, 2014, vol. 15, p. 21935-21946 | - |
dc.relation.uri | http://dx.doi.org/10.3390/ijms151221935 | - |
dc.rights | cc-by (c) Merino Montero, Susana et al., 2014 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Genètica, Microbiologia i Estadística) | - |
dc.subject.classification | Bacteris | - |
dc.subject.classification | Flagel·lats | - |
dc.subject.classification | Regulació genètica | - |
dc.subject.classification | Autoimmunitat | - |
dc.subject.other | Bacteria | - |
dc.subject.other | Flagellata | - |
dc.subject.other | Genetic regulation | - |
dc.subject.other | Autoimmunity | - |
dc.title | Role of Aeromonas hydrophila flagella glycosylation in adhesion to Hep-2 cells, biofilm formation and immune stimulation. | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 645555 | - |
dc.date.updated | 2015-01-12T15:34:44Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 25464381 | - |
Appears in Collections: | Articles publicats en revistes (Genètica, Microbiologia i Estadística) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
645555.pdf | 1.08 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License