Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/62905
Title: Selenomethionine incorporation into amyloid sequences regulates fibrillogenesis and toxicity.
Author: Martínez, Javier
Lisa, Silvia
Sánchez, Rosa
Kowalczyk, Wioleta
Zurita, Esther
Teixidó Turà, Meritxell
Giralt Lledó, Ernest
Andreu Martínez, David
Avila, Jesús
Gasset, María
Keywords: Biofísica
Síntesi de pèptids
Malalties neurodegeneratives
Aminoàcids
Citotoxicitat per mediació cel·lular
Polímers
Oxidació
Biophysics
Peptide synthesis
Neurodegenerative Diseases
Amino acids
Cell-mediated cytotoxicity
Polymers
Oxidation
Issue Date: 2011
Publisher: Public Library of Science (PLoS)
Abstract: The capacity of a polypeptide chain to engage in an amyloid formation process and cause a conformational disease is contained in its sequence. Some of the sequences undergoing fibrillation contain critical methionine (Met) residues which in vivo can be synthetically substituted by selenomethionine (SeM) and alter their properties.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0027999
It is part of: PLoS One, 2011, vol. 6, num. 11, p. e27999
Related resource: http://dx.doi.org/10.1371/journal.pone.0027999
URI: http://hdl.handle.net/2445/62905
ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (Química Inorgànica i Orgànica)

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