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Title: Prototypical Arthropod Gene Content and Genome Organisation in the Centipede Strigamia maritima
Author: Chipman, Ariel D.
Ferrier, David E. K.
Brena, Carlo
Qu, Jiaxin
Hughes, Daniel S. T.
Schröder, Reinhard
Torres-Oliva, Montserrat
Znassi, Nadia
Jiang, Huaiyang
Almeida, Francisca C.
Alonso, Claudio R.
Apostolou, Zivkos
Aqrawi, Peshtewani
Arthur, Wallace
Barna, Jennifer C. J.
Blankenburg, Kerstin P.
Brites, Daniela
Capella-Gutiérrez, Salvador
Coyle, Marcus
Dearden, Peter K.
Pasquier, Louis Du
Duncan, Elisabeth J.
Ebert, Dieter
Eibner, Cornelius
Erikson, Galina
Evans, Peter D.
Extavour, Cassandra G.
Francisco, Liezl
Gabaldón, Toni
Gillis, William J.
Goodwin-Horn, Elisabeth A.
Green, Jack E.
Griffiths-Jones, Sam
Grimmelikhuijzen, Cornelis J. P.
Gubbala, Sal
Guigó, Roderic
Han, Yi
Hauser, Frank
Havlak, Paul
Rozas Liras, Julio A.
Keywords: Genòmica
Genètica evolutiva
Genètica animal
Evolutionary genetics
Animal genetics
Issue Date: 25-Nov-2014
Publisher: Public Library of Science (PLoS)
Abstract: Myriapods (e.g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda is the only arthropod class not represented by a sequenced genome. We present an analysis of the genome of the centipede Strigamia maritima. It retains a compact genome that has undergone less gene loss and shuffling than previously sequenced arthropods, and many orthologues of genes conserved from the bilaterian ancestor that have been lost in insects. Our analysis locates many genes in conserved macro-synteny contexts, and many small-scale examples of gene clustering. We describe several examples where S. maritima shows different solutions from insects to similar problems. The insect olfactory receptor gene family is absent from S. maritima, and olfaction in air is likely effected by expansion of other receptor gene families. For some genes S. maritima has evolved paralogues to generate coding sequence diversity, where insects use alternate splicing. This is most striking for the Dscam gene, which in Drosophila generates more than 100,000 alternate splice forms, but in S. maritima is encoded by over 100 paralogues. We see an intriguing linkage between the absence of any known photosensory proteins in a blind organism and the additional absence of canonical circadian clock genes. The phylogenetic position of myriapods allows us to identify where in arthropod phylogeny several particular molecular mechanisms and traits emerged. For example, we conclude that juvenile hormone signalling evolved with the emergence of the exoskeleton in the arthropods and that RR-1 containing cuticle proteins evolved in the lineage leading to Mandibulata. We also identify when various gene expansions and losses occurred. The genome of S. maritima offers us a unique glimpse into the ancestral arthropod genome, while also displaying many adaptations to its specific life history.
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It is part of: PLoS Biology, 2014, vol. 12, num. 11, p. e1002005
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ISSN: 1544-9173
Appears in Collections:Articles publicats en revistes (Genètica, Microbiologia i Estadística)

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