Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/64744
Title: The relevance of theobromine for the beneficial effects of cocoa consumption.
Author: Martínez-Pinilla, Eva
Oñatibia-Astibia, Ainhoa
Franco Fernández, Rafael
Keywords: Cacau
Adenosina
Cafeïna
Malalties del sistema nerviós
Cocoa
Adenosine
Caffeine
Nervous System Diseases
Issue Date: 20-Feb-2015
Publisher: Frontiers Media
Abstract: Cocoa consumption began in America and in the mid sixteenth Century it quickly spread to Europe. Beyond being considered a pleasant habit due to its rich sweet lingering taste, chocolate was considered a good nutrient and even a medicine. Traditionally, health benefits of cocoa have been related with the high content of antioxidants of Theobroma cocoa beans. However, the direct psychoactive effect due to methylxanthines in cocoa is notable. Theobromine and caffeine, in the proportions found in cocoa, are responsible for the liking of the food/beverage. These compounds influence in a positive way our moods and our state of alertness. Theobromine, which is found in higher amounts than caffeine, seems to be behind several effects attributed to cocoa intake. The main mechanisms of action are inhibition of phosphodiesterases and blockade of adenosine receptors. Further mechanisms are being explored to better understand the health benefits associated to theobromine consumption. Unlike what happens in other mammals -pets- included, theobromine is safe for humans and has fewer unwanted effects than caffeine. Therefore, theobromine deserves attention as one of the most attractive molecules in cocoa.
Note: Reproducció del document publicat a: http://dx.doi.org/10.3389/fphar.2015.00030
It is part of: Frontiers in Pharmacology, 2015, vol. 6, p. 1-5
Related resource: http://dx.doi.org/10.3389/fphar.2015.00030
URI: http://hdl.handle.net/2445/64744
ISSN: 1663-9812
Appears in Collections:Articles publicats en revistes (Bioquímica i Biomedicina Molecular)

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