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Title: Osteolytic metastasis detected in a patient with lung carcinoma by F18-FDG PET
Author: González Sistal, Ángel
Baltasar Sánchez, Alicia
Sánchez Salmón, Aida
Ruibal Morell, Álvaro
Keywords: Càncer de pulmó
Diagnòstic per la imatge
Lung cancer
Diagnostic imaging
Issue Date: 10-Jul-2014
Abstract: We present a 53-year-old man with a vocal cord paralysis observed as a primary manifestation of lung carcinoma. Tc-99m MDP whole body bone scan was performed and resulted in a normal scintiscan. The bone scan did not reveal any suspicious foci of uptake. The possibility of bone metastasis was taken into consideration. A whole body F18-FDG-PET scan showed intense uptake in the left upper lung corresponding to the primary tumor. A bronchial biopsy confirmed infiltration by small cell lung carcinoma (SCLC). SCLC is composed of poorly differentiated, rapidly growing cells with diseases usually occurring centrally rather than peripherally. It metastasizes early. The whole-body F18-FDG-PET scan clearly demonstrated a focus of increased uptake in the second lumbar vertebral body suspicious for osteolytic metastasis. A lytic bone metastasis was confirmed by MRI. The patient then received therapy and underwent follow up abdominal CT. The scan showed blastic changes in the L2 vertebra suggesting response to treatment.
Note: Reproducció del document publicat a:
It is part of: Research, 2014, vol. 2014, num. 1, p. 1-3
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ISSN: 2334-1009
Appears in Collections:Articles publicats en revistes (Ciències Fisiològiques)

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