Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/67561
Title: Alanine aminotransferase: A target to improve utilisation of dietary nutrients in aquaculture
Author: Metón Teijeiro, Isidoro
Salgado Martín, María del Carmen
Anemaet, Ida Guurtje
González, Juan D.
Fernández González, Felipe Javier
Vázquez Baanante, Ma. Isabel
Keywords: Transferases
Suplements nutritius
Orada
Aqüicultura
Bioquímica
Biologia molecular
Transferases
Dietary supplements
Sparus aurata
Aquaculture
Biochemistry
Molecular biology
Issue Date: 2015
Publisher: Research Signpost
Abstract: Alanine aminotransferase (ALT) is a sensitive marker of dietary protein utilisation in fish. Three ALT isoforms (cALT1, cALT2 and mALT) encoded by two genes have been isolated from gilthead sea bream (Sparus aurata). Molecular characterization of ALT isozymes and gene promoters suggest involvement of cALT1 and mALT in postprandial use of dietary amino acids, while cALT2 seems associated to hepatic gluconeogenesis. Inhibition of hepatic cytosolic ALT activity stimulates pyruvate kinase and decreases the renewal rate of alanine in S. aurata. These findings point to ALT as a target to spare protein and improve catabolism of dietary carbohydrates in cultured fish.
Note: Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
Note: Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
It is part of: Recent Advances in Pharmaceutical Sciences V, 2015, Research Signpost. Editors: Diego Muñoz Torrero, M. Pilar Vinardell & Javier Palazón. ISBN: 978-81-308-0561-0. Chapter 9, p. 133-148.
Related resource: http://hdl.handle.net/2445/67430
URI: http://hdl.handle.net/2445/67561
Appears in Collections:Llibres / Capítols de llibre (Biologia Evolutiva, Ecologia i Ciències Ambientals)
Llibres / Capítols de llibre (Bioquímica i Biomedicina Molecular)

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