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http://hdl.handle.net/2445/68648
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DC Field | Value | Language |
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dc.contributor.author | Bestard Matamoros, Oriol | - |
dc.contributor.author | Campistol Plana, Josep M. | - |
dc.contributor.author | Morales, José M. | - |
dc.contributor.author | Sánchez-Fructuoso, A. | - |
dc.contributor.author | Cabello, Mercedes | - |
dc.contributor.author | Cabello, Virginia | - |
dc.contributor.author | Pallardó, Luis M. | - |
dc.contributor.author | Grinyó Boira, Josep M. | - |
dc.date.accessioned | 2016-01-11T13:13:09Z | - |
dc.date.available | 2016-01-11T13:13:09Z | - |
dc.date.issued | 2012-01-01 | - |
dc.identifier.issn | 0211-6995 | - |
dc.identifier.uri | http://hdl.handle.net/2445/68648 | - |
dc.description.abstract | The development of new immunosuppressants for renal transplantation is aimed not only at improving short-term outcomes, but also at achieving better safety, cardiovascular, and metabolic profiles and at decreasing nephrotoxicity. Belatacept is a fusion protein that inhibits T cell activation by binding to CD80 and CD86 antigens. Clinical trials, particularly the BENEFIT and BENEFIT-EXT studies, have shown that belatacept preserves function and structure in renal grafts. The effects of belatacept provide long-term, sustained results, and the safety and efficacy of this drug have been demonstrated in cases of renal transplantation from expanded criteria donors. Compared to calcineurin inhibitors, belatacept is associated with a lower incidence of chronic allograft nephropathy and a more favourable cardiovascular and metabolic profile. | - |
dc.format.extent | 11 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | spa | - |
dc.publisher | Elsevier España | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.3265/Nefrologia.pre2012.Jan.11176 | - |
dc.relation.ispartof | Nefrología, 2012, vol. 32, num. 3, p. 374-384 | - |
dc.relation.uri | http://dx.doi.org/10.3265/Nefrologia.pre2012.Jan.11176 | - |
dc.rights | cc-by-nc-nd (c) Sociedad Española de Nefrología, 2012 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Trasplantament renal | - |
dc.subject.classification | Immunosupressors | - |
dc.subject.classification | Factors de risc en les malalties | - |
dc.subject.classification | Cor | - |
dc.subject.other | Kidney transplantation | - |
dc.subject.other | Immunosupressive agents | - |
dc.subject.other | Risk factors in diseases | - |
dc.subject.other | Heart | - |
dc.title | Advances in immunosuppression for kidney transplantation: new strategies for preserving kidney function and reducing cardiovascular risk | - |
dc.title.alternative | Avances en la inmunosupresión para el trasplante renal. Nuevas estrategias para preservar la función renal y reducir el riesgo cardiovascular | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 621688 | - |
dc.date.updated | 2016-01-11T13:13:09Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) |
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File | Description | Size | Format | |
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621688.pdf | 90.95 kB | Adobe PDF | View/Open |
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