Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/68723
Title: Prevalence of Chagas Disease in Latin-American Migrants Living in Europe: A Systematic Review and Meta-analysis
Author: Requena-Méndez, Ana
Aldasoro, Edelweiss
Lazzari, Elisa de
Sicuri, Elisa
Brown, Michael
Moore, David A. J.
Gascón i Brustenga, Joaquim
Muñoz, José
Keywords: Malaltia de Chagas
Epidemiologia
Europa
Immigrants
Chagas' disease
Epidemiology
Europe
Immigrants
Issue Date: 13-Feb-2015
Publisher: Public Library of Science (PLoS)
Abstract: BACKGROUND: Few studies have assessed the burden of Chagas disease in non-endemic countries and most of them are based on prevalence estimates from Latin American (LA) countries that likely differ from the prevalence in migrants living in Europe. The aim of this study was to systematically review the existing data informing current understanding of the prevalence of Chagas disease in LA migrants living in European countries. METHODS: We conducted a systematic review and meta-analysis of studies reporting prevalence of Chagas disease in European countries belonging to the European Union (EU) before 2004 in accordance with the MOOSE guidelines and based on the database sources MEDLINE and Global Health. No restrictions were placed on study date, study design or language of publication. The pooled prevalence was estimated using random effect models based on DerSimonian & Laird method. RESULTS: We identified 18 studies conducted in five European countries. The random effect pooled prevalence was 4.2% (95%CI:2.2-6.7%); and the heterogeneity of Chagas disease prevalence among studies was high (I2 = 97%,p<0.001). Migrants from Bolivia had the highest prevalence of Chagas disease (18.1%, 95%CI:13.9-22.7%). CONCLUSIONS: Prevalence of Chagas in LA migrants living in Europe is high, particularly in migrants from Bolivia and Paraguay. Data are highly heterogeneous dependent upon country of origin and within studies of migrants from the same country of origin. Country-specific prevalence differs from the estimates available from LA countries. Our meta-analysis provides prevalence estimates of Chagas disease that should be used to estimate the burden of disease in European countries.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pntd.0003540
It is part of: PLoS Neglected Tropical Diseases, 2015, vol. 9, num. 2, p. e0003540
Related resource: http://dx.doi.org/10.1371/journal.pntd.0003540
URI: http://hdl.handle.net/2445/68723
ISSN: 1935-2727
Appears in Collections:Articles publicats en revistes (ISGlobal)

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