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Title: Plasmodium vivax Malaria in Pregnant Women in the Brazilian Amazon and the Risk Factors Associated with Prematurity and Low Birth Weight: A Descriptive Study
Author: Botto Menezes, Camila
Silva Dos Santos, Monica Carolina
Lopes Simplicio, Janicéia
Menezes de Medeiros, Janira
Barroso Gomes, Kelly Cristina
Carvalho Costa, Isabel Cristina de
Batista-Silva, Eva
Teixeira do Nascimento, Cristiana
Silva Chagas, Eda Cristina da
Jardim Sardinha, José Felipe
Simoes de Santana Filho, Franklin
Brock, Marianna
Bardají, Azucena
Martínez-Espinosa, Flor Ernestina
Keywords: Plasmodium vivax
Infants prematurs
Plasmodium vivax
Premature infants
Issue Date: 16-Dec-2015
Publisher: Public Library of Science (PLoS)
Abstract: INTRODUCTION: Plasmodium vivax is the most prevalent malaria species in the American region. Brazil accounts for the higher number of the malaria cases reported in pregnant women in the Americas. This study aims to describe the characteristics of pregnant women with malaria in an endemic area of the Brazilian Amazon and the risk factors associated with prematurity and low birth weight (LBW). METHODS/PRINCIPAL FINDINGS: Between December 2005 and March 2008, 503 pregnant women with malaria that attended a tertiary health centre were enrolled and followed up until delivery and reported a total of 1016 malaria episodes. More than half of study women (54%) were between 20-29 years old, and almost a third were adolescents. The prevalence of anaemia at enrolment was 59%. Most women (286/503) reported more than one malaria episode and most malaria episodes (84.5%, 846/1001) were due to P. vivax infection. Among women with only P. vivax malaria, the risk of preterm birth and low birth weight decreased in multigravidae (OR, 0.36 [95% CI, 0.16-0.82]; p = 0.015 and OR 0.24 [95% CI, 0.10-0.58]; p = 0.001, respectively). The risk of preterm birth decreased with higher maternal age (OR 0.43 [95% CI, 0.19-0.95]; p = 0.037) and among those women who reported higher antenatal care (ANC) attendance (OR, 0.32 [95% CI, 0.15-0.70]; p = 0.005). CONCLUSION: This study shows that P. vivax is the prevailing species among pregnant women with malaria in the region and shows that vivax clinical malaria may represent harmful consequences for the health of the mother and their offsprings particularly on specific groups such as adolescents, primigravidae and those women with lower ANC attendance.
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It is part of: PLoS One, 2015, vol. 10, num. 12, p. e0144399
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ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (ISGlobal)

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