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DC Field | Value | Language |
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dc.contributor.author | García-Basteiro, Alberto L. | - |
dc.contributor.author | López Varela, Elisa | - |
dc.contributor.author | Augusto, Orvalho | - |
dc.contributor.author | Gondo, Kizito | - |
dc.contributor.author | Muñoz, José | - |
dc.contributor.author | Sacarlal, Jahit | - |
dc.contributor.author | Marais, Ben J. | - |
dc.contributor.author | Alonso, Pedro | - |
dc.contributor.author | Ribo Aristizabal, Jose Luis | - |
dc.date.accessioned | 2016-02-04T12:52:31Z | - |
dc.date.available | 2016-02-04T12:52:31Z | - |
dc.date.issued | 2015-05-28 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://hdl.handle.net/2445/69242 | - |
dc.description.abstract | INTRODUCTION: Chest radiography remains a critical tool for diagnosing intrathoracic tuberculosis (TB) in young children who are unable to expectorate. We describe the radiological findings in children under 3 years of age investigated for TB in the district of Manhica, southern Mozambique, an area with a high prevalence of TB and HIV. METHODS: Digital antero-posterior and lateral projections were performed and reviewed by two independent readers, using a standardized template. Readers included a local pediatrician and a pediatric radiologist blinded to all clinical information. International consensus case definitions for intra-thoracic TB in children were applied. RESULTS: A total of 766 children were evaluated of whom 43 (5.6%) had TB. The most frequent lesion found in TB cases was air space consolidation (65.1%), followed by suggestive hilar lymphadenopathy (17.1%) and pleural effusion (7.0%). Air space consolidation was significantly more common in TB cases than in non-TB cases (odds ratio 8.9; 95% CI: 1.6-50.5), as were hilar lymphadenopathy (OR 17.2; 95% CI: 5.7-52.1). The only case with miliary infiltrates and 3 with pleural effusions occurred in HIV-infected children. CONCLUSION: Frequent air space consolidation complicates radiological distinction between TB and bacterial pneumonia in young children, underscoring the need for epidemiological contextualization and consideration of all relevant signs and symptoms. | - |
dc.format.extent | 12 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Public Library of Science (PLoS) | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0127323 | - |
dc.relation.isformatof | Correcció publicada a: http://doi.org/10.1371/journal.pone.0133338 | - |
dc.relation.ispartof | PloS one, 2015, vol. 10, num. 5, p. e0127323 | - |
dc.relation.ispartof | Correction: PLoS ONE, 2015, 10(5): e0127323 | - |
dc.relation.uri | http://dx.doi.org/10.1371/journal.pone.0127323 | - |
dc.rights | cc by (c) García-Basteiro et al., 2015 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | - |
dc.source | Articles publicats en revistes (ISGlobal) | - |
dc.subject.classification | Tuberculosi | - |
dc.subject.classification | Diagnòstic radiològic | - |
dc.subject.classification | Malalties dels infants | - |
dc.subject.classification | Moçambic | - |
dc.subject.classification | Radiografia | - |
dc.subject.other | Tuberculosis | - |
dc.subject.other | Radiography | - |
dc.subject.other | Radioscopic diagnosis | - |
dc.subject.other | Children's diseases | - |
dc.subject.other | Mozambique | - |
dc.title | Radiological findings in young children investigated for tuberculosis in Mozambique | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 685936 | - |
dc.date.updated | 2016-02-02T15:33:20Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 26020541 | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
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685936.pdf | 1.41 MB | Adobe PDF | View/Open | |
Correction_685934.PDF | Correction | 112.65 kB | Adobe PDF | View/Open |
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