Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/69244
Title: Proteins of Bartonella bacilliformis: Candidates for Vaccine Development
Author: Henriquez-Camacho, C.
Ventosilla, P.
Minnick, M.F.
Ruiz, Joaquim
Maguina, C.
Keywords: Malalties infeccioses
Vacunes
Bacteriologia mèdica
Amèrica del Sud
Communicable diseases
Vaccines
Medical bacteriology
South America
Issue Date: 6-Aug-2015
Publisher: Hindawi Publishing Corporation
Abstract: Bartonella bacilliformis is the etiologic agent of Carrion's disease or Oroya fever. B. bacilliformis infection represents an interesting model of human host specificity. The notable differences in clinical presentations of Carrion's disease suggest complex adaptations by the bacterium to the human host, with the overall objectives of persistence, maintenance of a reservoir state for vectorial transmission, and immune evasion. These events include a multitude of biochemical and genetic mechanisms involving both bacterial and host proteins. This review focuses on proteins involved in interactions between B. bacilliformis and the human host. Some of them (e.g., flagellin, Brps, IalB, FtsZ, Hbp/Pap31, and other outer membrane proteins) are potential protein antigen candidates for a synthetic vaccine.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1155/2015/702784
It is part of: International Journal of Peptides, 2015, vol. 2015, num. , p. 1-6
Related resource: http://dx.doi.org/10.1155/2015/702784
URI: http://hdl.handle.net/2445/69244
ISSN: 1687-9767
Appears in Collections:Articles publicats en revistes (ISGlobal)

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