Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/69245
Title: Trends in Cancer Incidence in Maputo, Mozambique, 1991-2008
Author: Lorenzoni, Cesaltina
Vilajeliu, Alba
Carrilho, Carla
Ismail, Mamudo R.
Castillo, Paola
Augusto, Orvalho
García-Basteiro, Alberto L.
Sidat, Mohsin
Sanjosé Llongueras, Silvia de
Menéndez, Clara
Ordi i Majà, Jaume
Keywords: Càncer
Epidemiologia
Moçambic
Factors de risc en les malalties
Cancer
Epidemiology
Mozambique
Risk factors in diseases
Issue Date: 25-Jun-2015
Publisher: Public Library of Science (PLoS)
Abstract: BACKGROUND: Very limited information is available regarding the incidence of cancer in sub-Saharan Africa. We analyzed changes in cancer patterns from 1991 to 2008 in Maputo (Mozambique). METHODS: We calculated the rates of incidence of different cancer sites by sex in the 5-year age-group of the population of Maputo city as well as age-standardized rates (ASRs) and average annual percentage changes (AAPC). RESULTS: Over the 18-year study period a total of 12,674 cases of cancer (56.9% females) were registered with an overall increase in the risk of cancer in both sexes. In males, the most common cancers were those of the prostate, Kaposi sarcoma (KS) and the liver. Prostate cancer showed the most dramatic increase over the whole study period (AAPC +11.3%; 95% CI: 9.7-13.0), with an ASR of 61.7 per 105 in 2003-2008. In females, the most frequent cancers were of the uterine cervix, the breast and KS, with the former increasing along the whole study period (AAPC + 4.7%; 95% CI: 3.4-6) with an ASR of 62.0 per 105 in 2003-2008 as well as breast cancer (AAPC +6.5%; 95%CI: 4.3-8.7). CONCLUSIONS: Overall, the risk of cancer rose in both sexes during the study period, particularly among cancers associated with westernization of lifestyles (prostate, breast), combined with increasingly rising incidences or limited changes in cancers associated with infection and poverty (uterine cervix, liver). Moreover, the burden of AIDS-associated cancers has shown a marked increase.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0130469
It is part of: PLoS One, 2015, vol. 10, num. 6, p. e0130469
Related resource: http://dx.doi.org/10.1371/journal.pone.0130469
URI: http://hdl.handle.net/2445/69245
ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (Fonaments Clínics)
Articles publicats en revistes (ISGlobal)

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